Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMXFBER)

Drug Name

KRH-102053 Drug Info

Synonyms

PHD2 activators (hypoxic cancer), Chonbuk National University/SK Chemicals

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Patented Agent(s)

Download the Complete Related Drug List

Drug(s) Targeting HIF-prolyl hydroxylase 2 (HPH-2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
FG-4592	DM4XSQ2	Anaemia	3A90	Phase 3	[2]
US9422240, 1-298	DMH7DL5	N. A.	N. A.	Patented	[3]
US8598210, Table XV, 2	DMDK98P	N. A.	N. A.	Patented	[4]
US8536181, A41	DMF9LNO	N. A.	N. A.	Patented	[5]
US8598210, Table XV, 5	DMEU5ST	N. A.	N. A.	Patented	[6]
US8536181, C17	DMRTL63	N. A.	N. A.	Patented	[7]
US8598210, Table XV, 4	DM3XWMO	N. A.	N. A.	Patented	[8]
US8921389, 210	DME1A80	N. A.	N. A.	Patented	[9]
US8536181, C35	DMAM51Z	N. A.	N. A.	Patented	[5]
US10100051, Compound 2	DMWESZ1	N. A.	N. A.	Patented	[10]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2833).
2	Crystalline forms of a prolyl hydroxylase inhibitor. US9115085.
3	Partially saturated nitrogen-containing heterocyclic compound. US9422240.
4	Prolyl hydroxylase inhibitors and methods of use. US9598370.
5	Prolyl hydroxylase inhibitors. US8536181.
6	Prolyl hydroxylase inhibitors and method of use. US8722895.
7	Methods for increasing the stabilization of hypoxia inducible factor-1 alpha. US8778412.
8	Prolyl hydroxylase inhibitors and methods of use. US8598210.
9	Naphthyridine derivatives as inhibitors of Hypoxia inducible factor (HIF) hydroxylase. US9695170.
10	Compound of 5-hydroxyl-1,7-naphthyridine substituted by aryloxy or heteroaryloxy, preparation method thereof and pharmaceutical use thereof. US10100051.