General Information of Drug (ID: DMXIDWE)

Drug Name
BAY-60-5521 Drug Info
Synonyms CETP inhibitors (dyslipidemia), Bayer; Cholesteryl ester transfer protein inhibitors (dyslipidemia), Bayer
Indication
Disease Entry ICD 11 Status REF
Arteriosclerosis BD40 Phase 1 [1]
Cross-matching ID
PubChem CID
11691871
CAS Number
CAS 893409-49-9
TTD Drug ID
DMXIDWE

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Discontinued Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Evacetrapib DMCDZ15 Cardiovascular disease BA00-BE2Z Phase 3 [3]
Dalcetrapib DMKNCVM Acute coronary syndrome BA41 Phase 3 [4]
Anacetrapib DMP2BFG Arteriosclerosis BD40 Phase 3 [5]
JTT-302 DMGLVBI Lipid metabolism disorder 5C52.Z Phase 2 [3]
DRL-17822 DMGD3XT Arteriosclerosis BD40 Phase 2 [3]
TA-8995 DMAZHT0 Cardiovascular disease BA00-BE2Z Phase 2 [6]
Torcetrapib DMDHYM7 Hyperlipidaemia 5C80 Discontinued in Phase 2 [7]
CETi-1 DMUG5OB Arteriosclerosis BD40 Discontinued in Phase 2 [8]
CP-800569 DMZ0YU7 Arteriosclerosis BD40 Discontinued in Phase 1 [9]
R7232 DMETAP8 Dyslipidemia 5C80-5C81 Discontinued in Phase 1 [4]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cholesteryl ester transfer protein (CETP) TTFQAYR CETP_HUMAN Inhibitor [2]

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034993)
2 Single dose pharmacokinetics, pharmacodynamics, tolerability and safety of BAY 60-5521, a potent inhibitor of cholesteryl ester transfer protein. Br J Clin Pharmacol. 2012 Feb;73(2):210-8.
3 The dyslipidaemia market. Nat Rev Drug Discov. 2014 Nov;13(11):807-8.
4 Clinical pipeline report, company report or official report of Roche (2009).
5 Assessment of a pharmacokinetic and pharmacodynamic interaction between simvastatin and anacetrapib, a potent cholesteryl ester transfer protein (C... Br J Clin Pharmacol. 2009 May;67(5):520-6.
6 Amgen To Acquire Privately-Held Dezima Pharma
7 Safety and tolerability of dalcetrapib. Am J Cardiol. 2009 Jul 1;104(1):82-91.
8 CETi-1. AVANT. Curr Opin Investig Drugs. 2004 Mar;5(3):334-8.
9 Pfizer. Product Development Pipeline. March 31 2009.