Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMXRIUT)

Drug Name

AMPSL Drug Info

Synonyms

Symlin-Fc-Leptin; Symlin-Fc-Leptin fusion protein (diabetes/obesity), Amprotein

Indication

Disease Entry	ICD 11	Status	REF
Diabetic complication	5A2Y	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Investigative Drug(s)

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Drug(s) Targeting Leptin receptor (LEPR)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Metreleptin	DM1NOEK	Acquired generalized lipodystrophy		Approved	[2]
AMPE4L	DM64X25	Diabetic complication	5A2Y	Investigative	[1]
PEGylated leptin	DMZ01PS	Obesity	5B81	Investigative	[1]
BL-5040	DMGULNZ	Cachexia	MG20	Investigative	[1]
ANG-2004	DMK1IMC	Obesity	5B81	Investigative	[1]
Leptin	DM5LY1H	Alzheimer disease	8A20	Investigative	[1]
EDP-21	DMMN0GO	Obesity	5B81	Investigative	[1]
AMPPL	DMVHOQE	Diabetic complication	5A2Y	Investigative	[1]
PEG-LPA-2	DMY293M	Solid tumour/cancer	2A00-2F9Z	Investigative	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1712).
2	2014 FDA drug approvals. Nat Rev Drug Discov. 2015 Feb;14(2):77-81.