Details of the Drug-Related molecule(s) Interaction Atlas

Ipsalazide Drug Info

Ipsalazida; Ipsalazida [Spanish]; Ipsalazide; Ipsalazide [BAN:INN]; Ipsalazide [INN:BAN]; Ipsalazido; Ipsalazido [Spanish]; Ipsalazidum; Ipsalazidum [Latin]; LS-36378; SCHEMBL596652; ZINC4216628; (E)-5-((4-(((Carboxymethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid; (E)-p-((3-Carboxy-4-hydroxyphenyl)azo)hippuric acid; 499H4332KZ; 80573-03-1; BX 650 A; BX-650A; Benzoic acid, 5-((4-(((carboxymethyl)amino)carbonyl)phenyl)azo)-2-hydroxy-, (E)-; CHEMBL2104872; SCHEMBL11165440; UNII-499H4332KZ

Cross-matching ID

PubChem CID

72003

CAS Number

CAS 80573-03-1

TTD Drug ID

DMYEM59

INTEDE Drug ID

DR2433

General Information of Drug (ID: DMYEM59)

Molecule-Related Drug Atlas

Molecule Type:

DME

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Discontinued Drug(s)

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Drug(s) Metabolized By Azoreductase (azoR)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Balsalazide	DM7I1T9	Inflammatory bowel disease	DD72	Approved	[1]
CTK0H-9987	DMSGYNP	N. A.	N. A.	Phase 2	[2]
SC-47085	DMGH4Q0	N. A.	N. A.	Phase 2	[3]
CB1954	DMVP4YK	Solid tumour/cancer	2A00-2F9Z	Discontinued in Phase 2	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug-Metabolizing Enzyme (DME)

References

1	Studies of two novel sulfasalazine analogs, ipsalazide and balsalazide. Dig Dis Sci. 1983 Jul;28(7):609-15.
2	The role of the gut flora in the metabolism of prontosil and neoprontosil in the rat. Xenobiotica. 1971 Mar;1(2):143-56.
3	Olsalazine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in inflammatory bowel disease. Drugs. 1991 Apr;41(4):647-64.
4	Discovery and evaluation of Escherichia coli nitroreductases that activate the anti-cancer prodrug CB1954. Biochem Pharmacol. 2010 Mar 1;79(5):678-87.