General Information of Drug (ID: DMYNIG5)

Drug Name
WS-070117 Drug Info
Indication
Disease Entry ICD 11 Status REF
Hyperlipidaemia 5C80 Investigative [1]
Cross-matching ID
PubChem CID
45377904
TTD Drug ID
DMYNIG5

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Drug(s) Targeting Lipoprotein lipase (LPL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [2]
Gemfibrozil DMD8Q3J Hyperlipidaemia 5C80 Approved [3]
AMT-011 DM8QIRN Blood forming organ disorder JB64.1 Phase 3 [1]
Ibrolipim DMOPWSX Hyperlipidaemia 5C80 Phase 2 [4]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Lipoprotein lipase (LPL) TTOF3WZ LIPL_HUMAN Modulator [1]

References

1 Alipogene tiparvovec for the treatment of lipoprotein lipase deficiency. Drugs Today (Barc). 2013 Mar;49(3):161-70.
2 Effects of clofibrate treatment in laying hens. Poult Sci. 2007 Jun;86(6):1187-95.
3 Mode of action of fibrates in the regulation of triglyceride and HDL-cholesterol metabolism. Drugs Today (Barc). 2006 Jan;42(1):39-64.
4 NO-1886 (ibrolipim), a lipoprotein lipase activator, increases the expression of uncoupling protein 3 in skeletal muscle and suppresses fat accumulation in high-fat diet-induced obesity in rats. Metabolism. 2005 Dec;54(12):1587-92.