Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMYPXQ2)

Drug Name

CVBT-141H Drug Info

Synonyms

CVBT-141A; CVBT-141C; CVBT-141C); Cardio Vascu-Grow; FGF-1-141; Recombinant FGF-1 (coronary heart disease), CardioVascular Therapeutics; Recombinant FGF-1 (peripheral vascular disease), CardioVascular biotherapeutics

Indication

Disease Entry	ICD 11	Status	REF
Coronary artery disease	BA80	Phase 2	[1]
Coronary heart disease	BA80.Z	Phase 2	[2]
Peripheral arterial disease	BD4Z	Phase 2	[2]

Cross-matching ID

TTD Drug ID: DMYPXQ2

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Discontinued Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Heparin-binding growth factor 1 (FGF1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Riferminogene pecaplasmid	DMBKN4P	Critical limb ischemia	BD4Y	Discontinued in Phase 3	[4]
Formic Acid	DMNFZC6	Discovery agent	N.A.	Investigative	[5]
N,O6-Disulfo-Glucosamine	DMYCV7U	Discovery agent	N.A.	Investigative	[5]
O2-Sulfo-Glucuronic Acid	DME78MS	Discovery agent	N.A.	Investigative	[5]
Naphthalene Trisulfonate	DML6FI3	Discovery agent	N.A.	Investigative	[5]
5-AMINO-NAPHTALENE-2-MONOSULFONATE	DMYTUNE	Discovery agent	N.A.	Investigative	[6]
Sucrose Octasulfate	DMET64R	Discovery agent	N.A.	Investigative	[5]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Heparin-binding growth factor 1 (FGF1)	TTMY81X	FGF1_HUMAN	Modulator	[3]

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020529)
2	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3	Clinical pipeline report, company report or official report of CVBT.
4	Riferminogene pecaplasmide. Am J Cardiovasc Drugs. 2010;10(5):343-6.
5	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
6	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.