General Information of Drug (ID: DMZYKXN)

Drug Name
PT320 Drug Info
Indication
Disease Entry ICD 11 Status REF
Parkinson disease 8A00.0 Phase 2 [1]
Cross-matching ID
TTD Drug ID
DMZYKXN

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Drug(s) Targeting Glucagon (GCG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
PB-1023 DMZCI04 Type-2 diabetes 5A11 Phase 2 [3]
MK-8521 DMVNAYE Type-2 diabetes 5A11 Phase 2 [3]
JNJ-64565111 DMVSUH1 Obesity 5B81 Phase 2 [3]
MEDI0382 DMSV60C Type-2 diabetes 5A11 Phase 2 [3]
SAR425899 DM53IPE Diabetic complication 5A2Y Phase 1 [3]
ZP2929 DMRVDUM Type-1 diabetes 5A10 Phase 1 [3]
⏷ Show the Full List of 6 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glucagon (GCG) TT0NUFM GLUC_HUMAN Agonist [2]

References

1 ClinicalTrials.gov (NCT04269642) Phase IIa Study to Evaluate the Efficacy and Safety of Subcutaneous SR-Exenatide (PT320) in Patients With Early Parkinson's Disease. U.S.National Institutes of Health.
2 Sustained Release GLP-1 Agonist PT320 Delays Disease Progression in a Mouse Model of Parkinson's Disease. ACS Pharmacol Transl Sci. 2021 Mar 16;4(2):858-869.
3 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)