Details of the Drug

General Information of Drug (ID: DMRVDUM)

Drug Name
ZP2929
Indication
Disease Entry ICD 11 Status REF
Type-1 diabetes 5A10 Phase 1 [1]
Diabetic complication 5A2Y Preclinical [2]
Obesity 5B81 Preclinical [2]
Cross-matching ID
TTD ID
D0FW0B
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glucagon (GCG) TT0NUFM GLUC_HUMAN Agonist [1]
Glucagon receptor (GCGR) TT9O6WS GLR_HUMAN Modulator [3]
Glucagon-like peptide 1 receptor (GLP1R) TTVIMDE GLP1R_HUMAN Modulator [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Type-1 diabetes
ICD Disease Classification 5A10
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Glucagon-like peptide 1 receptor (GLP1R) DTT GLP1R 1.25E-01 0.17 1.26
Glucagon receptor (GCGR) DTT GCGR 7.24E-02 -0.52 -0.92
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 2011 Pipeline of Zealand Pharma.
3 Company report (Zealandpharma)