Details of the Drug Reposition

General Information of This Drug (ID: DM9BI7M)

Drug Name
Duloxetine   DM9BI7M
Synonyms
Yentreve; LY 248686; Cymbalta (TN); Duloxetine (INN); Duloxetine [INN:BAN]; Yentreve (TN); Duloxetine, (+)-isomer; (3S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine; (3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(2-thienyl)propan-1-amine; (3S)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine; (S)-Duloxetine; (S)-N-Methyl-gamma-(1-naphthalenyloxy)-2-thiophenepropanamine
Therapeutic Class
Antidepressants
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)
3 Approved Indication(s)
Indication Name Indication ID ICD-11 Status REF
Major depressive disorder DIS4CL3X 6A70.3 Approved [1]
Stress urinary incontinence DISFW74P MF50.20 Approved [1]
Traumatic brain injury DISN8K9H NA07.Z Approved [1]
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1 Withdrawn Indication(s)
Indication Name Indication ID ICD-11 Status REF
Fibromyalgia DISZJDS2 MG30.01 Withdrawn [2]
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1 Discontinued in Phase 2 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Generalized anxiety disorder DISPSQCW 6B00 Discontinued in Phase 2 [3]
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References

1 Duloxetine FDA Label
2 A Study of 3 Doses of Tiotropium Hydrofluoralkane (HFA) Breath Actuated Inhaler (BAI), in Patients With Chronic Obstructive Pulmonary Disease
3 Dose-finding Study Using Pentostatin for Injection in the Treatment of Steroid-refractory aGvHD