Details of the Drug Reposition

General Information of This Drug (ID: DM9G7BS)

• Drug Name: Cyclizine (DM9G7BS)
• Synonyms: Ciclizina; Cyclizinum; Emoquil; Marezine; Nautazine; Valoid; Wellcome; Cyclizine chloride; Cyclizine hydrochloride; Marezine hydrochloride; BW 47-83; Ciclizina [INN-Spanish]; Cyclizine (INN); Cyclizinum [INN-Latin]; Emoquil (TN); Marezine (TN); Marzine (TN); Ne-devomit; Neo-devomit; Reis-fit; Valoid (TN); Wellcome preparation 47-83; Wellcome prepn 47-83; Cyclizine [INN:BAN:DCF]; Wellcome prepn. 47-83; N-Benzhydryl-N'-methylpiperazine; N-Methyl-N'-benzhydrylpiperazine; N-Methyl-N'-benzyhydrylpiperazine; (+-)-1-diphenylmethyl-4-methylpiperazine; (-)-1-Diphenylmethyl-4-methylpiperazine; (N-Benzhydryl)(N'-methyl)diethylenediamine; 1-(Diphenylmethyl)-4-methylpiperazine; 1-Benzhydryl-4-methylpiperazin; 1-Benzhydryl-4-methylpiperazine; 1-Diphenylmethyl-4-methylpiperazine
• Therapeutic Class: Antiemetics
• Drug Type: Small molecular drug

Information on Drug Reposition of This Drug

4 Approved Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Common cold	DIS3MADM	CA00	Approved	[1]
Vasomotor/allergic rhinitis	DISHSTQ0	CA08	Approved	[1]
Cough	DIS51FA4	MD12	Approved	[1]
Nausea	DIS50TOO	MD90	Approved	[2]

2 Withdrawn Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Allergic conjunctivitis	DISZ5ZJN	9A60.02	Withdrawn	[3]
Motion sickness	DISZ2WZW	NF08.3	Withdrawn	[4]

References

• [1] Cyclizine FDA Label
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7151).
• [3] Gemcitabine Hydrochloride and Cisplatin or High-Dose Methotrexate, Vinblastine, Doxorubicin Hydrochloride, and Cisplatin in Treating Patients With Urothelial Cancer
• [4] Influence of Atorvastatin on Psoriasis Severity and Endothelial Function