Details of the Drug Reposition

General Information of This Drug (ID: DMEMV9D)

• Drug Name: Trimeprazine (DMEMV9D)
• Synonyms: Alimemazina; Alimemazine; Alimemazinum; Alimezine; Isobutrazine; Methylpromazine; Oxomemazin; Repetin; Teralen; Trimeperazine; Trimeprazine Tartrat; Bayer 1219; Alimemazina [INN-Spanish]; Alimemazine (INN); Alimemazine [INN:BAN]; Alimemazinum [INN-Latin]; Dl-Trimeprazine; Nedeltran (TN); Oxomemazine [DCF:INN]; Panectyl (TN); Repeltin (TN); Temaril (TN); Therafene (TN); Theralen (TN); Theralene (TN); Trimeprazine (BAN); Vallergan (TN); Vanectyl (TN); Trimeprazine 5,5-dioxide; Trimeprazine hemi-(+)-tartrate; N,N,beta-Trimethyl-10H-phenothiazine-10-propanamine; N,N,2-trimethyl-3-phenothiazin-10-ylpropan-1-amine; N,N,2-trimethyl-3-(10H-phenothiazin-10-yl)propan-1-amine; (+-)-Alimemazine; (+-)-Trimeprazine; 10-(2-Methyl-3-dimethylaminopropyl)-phenothiazine; 10-(3-(Dimethylamino)-2-methylpropyl)phenothiazine; 10-(3-Dimethylamino-2-methylpropyl)phenothiazine
• Therapeutic Class: Antihistamines
• Drug Type: Small molecular drug

Information on Drug Reposition of This Drug

3 Approved Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Angioedema	DIS90QDN	4A00.15	Approved	[1]
Allergic rhinitis	DIS3U9HN	CA08.0	Approved	[2]
Urticaria	DIS9WQAI	EB00-EB05	Approved	[1]

1 Withdrawn Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Allergic conjunctivitis	DISZ5ZJN	9A60.02	Withdrawn	[3]

1 Investigative Indication(s)

Indication Name	Indication ID	ICD-11	Status	REF
Pruritus	DISVH62W	EC90	Investigative	[1]

References

• [1] Trimeprazine FDA Label
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7237).
• [3] A Study to Evaluate Topical Phenylephrine Gel in the Management of Faecal Incontinence