Details of the Drug Reposition

General Information of This Drug (ID: DMHZV7X)

Drug Name
Golimumab   DMHZV7X
Synonyms Simponi (TN); Golimumab (USAN/INN)
Drug Type
Antibody

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)
3 Approved Indication(s)
Indication Name Indication ID ICD-11 Status REF
Ulcerative colitis DIS8K27O DD71 Approved [1]
Rheumatoid arthritis DISTSB4J FA20 Approved [2]
Psoriatic arthritis DISLWTG2 FA21 Approved [3]
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1 Phase 2/3 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Inflammatory bowel disease DISGN23E DD72 Phase 2/3 [4]
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1 Discontinued in Phase 1 Indication(s)
Indication Name Indication ID ICD-11 Status REF
Ankylosing spondylitis DISRC6IR FA92.0 Discontinued in Phase 1 [5]
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References

1 Efficacy and safety of biologics and small molecule drugs for patients with moderate-to-severe ulcerative colitis: a systematic review and network meta-analysis. Lancet Gastroenterol Hepatol. 2022 Feb;7(2):161-170.
2 ClinicalTrials.gov (NCT02390700) Observational Study of Golimumab Intravenous Infusion
3 Efficacy and safety of biologics in psoriatic arthritis: a systematic literature review and network meta-analysis. RMD Open. 2020 Feb;6(1):e001117.
4 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6776).
5 Iododoxorubicin in Treating Patients With Primary Systemic Amyloidosis