Details of the Drug Reposition

General Information of This Drug (ID: DMKB9FI)

Drug Name
Benzoic Acid   DMKB9FI
Synonyms
Phenylformate; benzoate anion; Benzoic acid, ion(1-); 766-76-7; Benzeneformate; Tennplas; Phenylcarboxylate; Benzenemethanoate; Retarded BA; Benzenecarboxylate; Phenyl carboxylic acid; benzoic acid anion; Oracyclic acid; 4-Carboxybenzenide; Benzene formic acid; AC1Q1HDY; AC1Q22CA; AC1L18SS; GTPL4565; DTXSID4043771; CHEBI:16150; BDBM36181; CTK2H9612; WPYMKLBDIGXBTP-UHFFFAOYSA-M; STL483236; ZINC328578076; NCGC00247905-01; ZB000218; CJ-00025; LS-190261; 3230-EP2374454A1; 3230-EP2372017A1; 3230-EP2316825A1; 3230-EP2316457A1
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)
4 Approved Indication(s)
Indication Name Indication ID ICD-11 Status REF
Mycoses DIS9K7PB 1F2Z Approved [1]
Dermatomyositis DIS50C5O 4A41.0 Approved [2]
Ornithine transcarbamylase deficiency DIS3DOIC 5C50.AY Approved [3]
Alopecia areata DIS0XXBJ ED70.2 Approved [4]
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1 Withdrawn Indication(s)
Indication Name Indication ID ICD-11 Status REF
Pemphigus DISZAZ6M N.A. Withdrawn [5]
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2 Investigative Indication(s)
Indication Name Indication ID ICD-11 Status REF
Peyronie disease DISUZ8RQ N.A. Investigative [6]
Scleroderma DISVQ342 4A42 Investigative [7]
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References

1 Synergistic effect of antioxidant system and osmolyte in hydrogen sulfide and salicylic acid crosstalk-induced heat tolerance in maize (Zea mays L.) seedlings. Plant Signal Behav. 2015;10(9):e1051278.
2 Benzoic acid production via cascade biotransformation and coupled fermentation-biotransformation. Biotechnol Bioeng. 2020 Aug;117(8):2340-2350.
3 Ornithine transcarbamylase deficiency: a urea cycle defect. Eur J Paediatr Neurol. 2003;7(3):115-21.
4 Benzoic acid and its derivatives as naturally occurring compounds in foods and as additives: Uses, exposure, and controversy. Crit Rev Food Sci Nutr. 2017 Sep 22;57(14):3084-3103.
5 Study of a Potential New Treatment for Patients With Toxic Epidermal Necrolysis (TEN)
6 Safety Assessment of Benzyl Alcohol, Benzoic Acid and its Salts, and Benzyl Benzoate. Int J Toxicol. 2017 Nov/Dec;36(3_suppl):5S-30S.
7 The intracellular chloride channel 4 (CLIC4) activates systemic sclerosis fibroblasts. Rheumatology (Oxford). 2021 Sep 1;60(9):4395-4400.