Details of the Drug Reposition

General Information of This Drug (ID: DMRJ3YX)

Drug Name
Alteplase   DMRJ3YX
Synonyms Activase (TN)
Therapeutic Class
Thrombolytic Agents

Information on Drug Reposition of This Drug

Molecular Interaction Atlas (MIA)
2 Approved Indication(s)
Indication Name Indication ID ICD-11 Status REF
Acute myocardial infarction DISE3HTG BA41 Approved [1]
Pulmonary embolism DISJYP9B BB00 Approved [2]
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1 Withdrawn Indication(s)
Indication Name Indication ID ICD-11 Status REF
Ischemic stroke DISYV7YJ 8B11.5Z Withdrawn [3]
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References

1 Single-bolus tenecteplase compared with front-loaded alteplase in acute myocardial infarction: the ASSENT-2 double-blind randomised trial. Lancet. 1999 Aug 28;354(9180):716-22.
2 Emerging drugs in peripheral arterial disease. Expert Opin Emerg Drugs. 2006 Mar;11(1):75-90.
3 Iloprost for Bridging to Heart Transplantation in PH