Details of the Drug

General Information of Drug (ID: DM0PWX2)

Drug Name
AUTO2
Indication
Disease Entry ICD 11 Status REF
Multiple myeloma 2A83 Phase 1/2 [1]
Drug Type
CAR T Cell Therapy
Cross-matching ID
TTD ID
D0B8UW

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
B-cell maturation protein (TNFRSF17) TTZ3P4W TNR17_HUMAN CAR-T-Cell-Therapy(Dual specific) [1]
Transmembrane activator and CAML interactor (TNFRSF13B) TTL9OD4 TR13B_HUMAN CAR-T-Cell-Therapy(Dual specific) [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT03287804) APRIL CAR T Cells (AUTO2) Targeting BCMA and TACI for the Treatment of Multiple Myeloma