Details of the Drug

General Information of Drug (ID: DM14NKM)

Drug Name

Triiodothyronine

Synonyms

liothyronine; triiodothyronine; 3,3',5-Triiodo-L-thyronine; 6893-02-3; Liothyronin; Tresitope; 3,5,3'-triiodothyronine; L-Liothyronine; O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine; 3,5,3'-Triiodo-L-thyronine; triothyrone; Liothyroninum; Lyothyronine; Liotironina; T3; L-T3; 3,3',5-Triiodothyronine; Triiodo-L-thyronine; 3,5,3'TRIIODOTHYRONINE; L-3,5,3'-Triiodothyronine; T3 (amino acid); T3 (Hormone); L-3,3',5-TriioDOThyronine; Liothyronine [INN:BAN]; Li; Liothyronine

Indication

Disease Entry	ICD 11	Status	REF
Euthyroid goiter	5A01.1	Approved	[1]
Coronavirus Disease 2019 (COVID-19)	1D6Y	Phase 2	[2]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C15H12I3NO4
Canonical SMILES: C1=CC(=C(C=C1OC2=C(C=C(C=C2I)CC(C(=O)O)N)I)I)O
InChI: 1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1
InChIKey: AUYYCJSJGJYCDS-LBPRGKRZSA-N

Cross-matching ID

PubChem CID: 5920
ChEBI ID: CHEBI:18258
CAS Number: 15785-49-6
TTD ID: D07NPX

Combinatorial Drugs (CBD)

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Repurposed Drugs (RPD)

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References

1	FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 076923.
2	ClinicalTrials.gov (NCT04348513) Triiodothyronine for the Treatment of Critically Ill Patients With COVID-19 Infection. U.S. National Institutes of Health.