Details of the Drug Combinations

General Information of This Drug (ID: DM14NKM)

Drug Name
Triiodothyronine   DM14NKM
Synonyms
liothyronine; triiodothyronine; 3,3',5-Triiodo-L-thyronine; 6893-02-3; Liothyronin; Tresitope; 3,5,3'-triiodothyronine; L-Liothyronine; O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine; 3,5,3'-Triiodo-L-thyronine; triothyrone; Liothyroninum; Lyothyronine; Liotironina; T3; L-T3; 3,3',5-Triiodothyronine; Triiodo-L-thyronine; 3,5,3'TRIIODOTHYRONINE; L-3,5,3'-Triiodothyronine; T3 (amino acid); T3 (Hormone); L-3,3',5-TriioDOThyronine; Liothyronine [INN:BAN]; Li; Liothyronine
Indication
Disease Entry ICD 11 Status REF
Euthyroid goiter 5A01.1 Approved [1]
Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 2 [2]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

82 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Triiodothyronine DCH45RX 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acamprosate + Triiodothyronine DCXPNJH Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetohydroxamic Acid + Triiodothyronine DCUNY8V Acetohydroxamic Acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Auranofin + Triiodothyronine DCBB2FG Auranofin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
BIO-300 + Triiodothyronine DC966JR BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Bortezomib + Triiodothyronine DCLCBWL Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Brincidofovir + Triiodothyronine DCD9SDL Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Buspirone + Triiodothyronine DC02MA5 Buspirone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Cefmenoxime + Triiodothyronine DCK9IRR Cefmenoxime Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Cerivastatin + Triiodothyronine DC7USSG Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Cevimeline + Triiodothyronine DCP2H0N Cevimeline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Chloroquine + Triiodothyronine DCWVRT5 Chloroquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Chlorzoxazone + Triiodothyronine DCC7GDL Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Cilostazol + Triiodothyronine DCWF6VF Cilostazol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Cinacalcet + Triiodothyronine DCHI660 Cinacalcet Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Crotamiton + Triiodothyronine DCTKGFQ Crotamiton Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Cytarabine + Triiodothyronine DCK6T5Z Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Docetaxel + Triiodothyronine DCPUKBZ Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dopamine + Triiodothyronine DC0Z90N Dopamine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Epinephrine + Triiodothyronine DCN3F4P Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Ezetimibe + Triiodothyronine DCI7L0X Ezetimibe Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Flavonoid derivative 1 + Triiodothyronine DC2VQPG Flavonoid derivative 1 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Furazolidone + Triiodothyronine DCX3HEH Furazolidone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Hyodeoxycholic acid + Triiodothyronine DCOSN81 Hyodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Triiodothyronine DCRL766 Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mebendazole + Triiodothyronine DCWZ13V Mebendazole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mefloquine + Triiodothyronine DCR5DAQ Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methylergonovine + Triiodothyronine DCXSQ2M Methylergonovine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mycophenolic acid + Triiodothyronine DCEVHIL Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Nizatidine + Triiodothyronine DCOB1R7 Nizatidine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Oseltamivir + Triiodothyronine DCOII6T Oseltamivir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pazopanib HCl + Triiodothyronine DC48O2F Pazopanib HCl Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pramipexole + Triiodothyronine DC8SA46 Pramipexole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Procarbazine + Triiodothyronine DCUZ1OL Procarbazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Ramelteon + Triiodothyronine DCUJSHG Ramelteon Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tamoxifen + Triiodothyronine DCBBI8U Tamoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Gefitinib DC4KXOZ Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Paromomycin DCWRHYX Paromomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Dantrolene DC7RFWB Dantrolene Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Diethylcarbamazine DCI3K3H Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Chlorphenesin DCG4M9Y Chlorphenesin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + PMID28460551-Compound-2 DCGH34I PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Methotrexate DCN5JNX Methotrexate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Repaglinide DCD0BG4 Repaglinide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Vinblastine DCKZ6YX Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Anamorelin DCUIWZJ Anamorelin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Triapine DCX82UD Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Rifampin DC13GXP Rifampin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + IT-141 DCCK1K4 IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Metyrosine DCGOHIJ Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Efavirenz DCCGGIF Efavirenz Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Testosterone cypionate DCNLJO6 Testosterone cypionate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Armodafinil DC1NSOL Armodafinil Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Pentamidine DC0ZY6N Pentamidine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Arfolitixorin DCXRTSM Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Eflornithine DCH1JIC Eflornithine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + PF-02545920 DC4XQS7 PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Isoproterenol DCXM5OW Isoproterenol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Etonogestrel DCCEFIT Etonogestrel Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Trifluoperazine DCYCRPP Trifluoperazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Methocarbamol DCLV5KX Methocarbamol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Darunavir DCWIPDL Darunavir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Methylene blue DCAIL5G Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Acamprosate DCDJ6YQ Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Enalaprilat DCUW737 Enalaprilat Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Oxyphenbutazone DCUUCL5 Oxyphenbutazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Leflunomide DC6HNSP Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Quinine DC87Y11 Quinine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Mycophenolic acid DCGC2EZ Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Oxandrolone DCWL6ZJ Oxandrolone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Doxorubicin DCC34S8 Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Nitisinone DCCEKY4 Nitisinone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Silver sulfadiazine DC0W52K Silver sulfadiazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Sumatriptan DCQBDDG Sumatriptan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + FORMESTANE DC4TZU6 FORMESTANE Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Cerivastatin DCGONPD Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Aciclovir DC7ZB82 Aciclovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triiodothyronine + Azatadine DCMMUKK Azatadine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trimethobenzamide + Triiodothyronine DCQR50C Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tropisetron + Triiodothyronine DCKQRIB Tropisetron Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Vorinostat + Triiodothyronine DCCIHH7 Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
VR-776 + Triiodothyronine DC3VWSL VR-776 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
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References

1 FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 076923.
2 ClinicalTrials.gov (NCT04348513) Triiodothyronine for the Treatment of Critically Ill Patients With COVID-19 Infection. U.S. National Institutes of Health.
3 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.