General Information of Drug (ID: DM180DM)

Drug Name
ARGX-113
Indication
Disease Entry ICD 11 Status REF
Myasthenia gravis 8C6Y Phase 3 [1]
Drug Type
Small molecular drug
Cross-matching ID
TTD ID
DZA98D

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Neonatal Fc receptor (FCGRT) TTKLPHO FCGRN_HUMAN Antagonist [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT03770403) A Safety and Tolerability Study of ARGX-113 in Patients With Myasthenia Gravis Who Have Generalized Muscle Weakness. (ADAPT+). U.S. National Institutes of Health.
2 Randomized phase 2 study of FcRn antagonist efgartigimod in generalized myasthenia gravis. Neurology. 2019 Jun 4;92(23):e2661-e2673.