Details of the Drug

General Information of Drug (ID: DM2HLGC)

• Drug Name: DZ9
• Synonyms: CHEMBL1084955; 3-amino-N-(3-fluorophenyl)-6-thiophen-2-ylthieno[2,3-b]pyridine-2-carboxamide; 3hfj; NadD inhibitor 3_02; AC1MMP3S; SCHEMBL11887601; HMS1801K16; RSC004746; BDBM50318653; NCGC00100444-01; EU-0014464; US8785499, 3_02; 3-amino-N-(3-fluorophenyl)-6-(thiophen-2-yl)thieno[2,3-b]pyridine-2-carboxamide; DZ9
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 369.4
  Logarithm of the Partition Coefficient (xlogp); 4.7
  Rotatable Bond Count (rotbonds); 3
  Hydrogen Bond Donor Count (hbonddonor); 2
  Hydrogen Bond Acceptor Count (hbondacc); 6
• Chemical Identifiers:
  Formula: C18H12FN3OS2
  IUPAC Name: 3-amino-N-(3-fluorophenyl)-6-thiophen-2-ylthieno[2,3-b]pyridine-2-carboxamide
  Canonical SMILES: C1=CC(=CC(=C1)F)NC(=O)C2=C(C3=C(S2)N=C(C=C3)C4=CC=CS4)N
  InChI: InChI=1S/C18H12FN3OS2/c19-10-3-1-4-11(9-10)21-17(23)16-15(20)12-6-7-13(22-18(12)25-16)14-5-2-8-24-14/h1-9H,20H2,(H,21,23)
  InChIKey: UCTSEHMMSSIODN-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 3289443
  TTD ID: D0A0BS

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bacterial Nicotinate-nucleotide adenylyltransferase (Bact nadD)	TT1NFO3	NADD_ECOLI	Inhibitor	[1]

References

• [1] Targeting NAD biosynthesis in bacterial pathogens. US8785499.