Details of the Drug-Related molecule(s) Interaction Atlas

DZ9 Drug Info

CHEMBL1084955; 3-amino-N-(3-fluorophenyl)-6-thiophen-2-ylthieno[2,3-b]pyridine-2-carboxamide; 3hfj; NadD inhibitor 3_02; AC1MMP3S; SCHEMBL11887601; HMS1801K16; RSC004746; BDBM50318653; NCGC00100444-01; EU-0014464; US8785499, 3_02; 3-amino-N-(3-fluorophenyl)-6-(thiophen-2-yl)thieno[2,3-b]pyridine-2-carboxamide; DZ9

Cross-matching ID

PubChem CID

3289443

TTD Drug ID

DM2HLGC

General Information of Drug (ID: DM2HLGC)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

Investigative Drug(s)

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Drug(s) Targeting Bacterial Nicotinate-nucleotide adenylyltransferase (Bact nadD)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
AC1LJNG0	DM9Q0EC	N. A.	N. A.	Patented	[1]
STK696827	DM19GAY	N. A.	N. A.	Patented	[1]
Nicotinamide-Adenine-Dinucleotide	DM9LRKB	N. A.	N. A.	Investigative	[2]
Deamido-NAD	DMDFRTI	N. A.	N. A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bacterial Nicotinate-nucleotide adenylyltransferase (Bact nadD)	TT1NFO3	NADD_ECOLI	Inhibitor	[1]

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References

1	Targeting NAD biosynthesis in bacterial pathogens. US8785499.
2	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
3	Crystal structures of E. coli nicotinate mononucleotide adenylyltransferase and its complex with deamido-NAD. Structure. 2002 Jan;10(1):69-79.