Details of the Drug

General Information of Drug (ID: DM35YFC)

Drug Name

MS-1819

Synonyms

Recombinant lipase (exocrine pancreatic insufficiency), Laboratoires Mayoly Spindler

Indication

Disease Entry	ICD 11	Status	REF
Exocrine pancreatic insufficiency	DC35.1	Phase 1/2	[1]
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Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski): 0

Molecular Weight (mw)

277.4

Logarithm of the Partition Coefficient (xlogp)

4.1

Rotatable Bond Count (rotbonds)

4

Hydrogen Bond Donor Count (hbonddonor)

0

Hydrogen Bond Acceptor Count (hbondacc)

3

Chemical Identifiers

Formula: C16H23NOS
IUPAC Name: N-[(4-tert-butylphenyl)methoxy]thian-4-imine
Canonical SMILES: CC(C)(C)C1=CC=C(C=C1)CON=C2CCSCC2
InChI: InChI=1S/C16H23NOS/c1-16(2,3)14-6-4-13(5-7-14)12-18-17-15-8-10-19-11-9-15/h4-7H,8-12H2,1-3H3
InChIKey: QKZIKPBOHKELOB-UHFFFAOYSA-N

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Pancreatic triacylglycerol lipase (PNLIP)	TTXMY0J	LIPP_HUMAN	Modulator	[2]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800030334)
2	Clinical pipeline report, company report or official report of AzurRx.