Details of the Drug

General Information of Drug (ID: DM3DHWE)

Drug Name

SAR442970

Indication

Disease Entry	ICD 11	Status	REF
Inflammation	1A00-CA43.1	Phase 1	[1]
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Drug Type

Nanobody

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
TAX transcriptionally-activated glycoprotein 1 (OX40)	TTBW580	TNFL4_HUMAN	Not Available	[1]
Tumor necrosis factor (TNF)	TTF8CQI	TNFA_HUMAN	Not Available	[1]

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Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Inflammation

ICD Disease Classification

1A00-CA43.1

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Tumor necrosis factor (TNF)	DTT	TNF	8.51E-01	0.05	0.27

Molecular Expression Atlas (MEA)

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References

1	Clinical pipeline report, company report or official report of Sanofi