Details of the Drug

General Information of Drug (ID: DM4LR0Y)

Drug Name
GSK-958108
Indication
Disease Entry ICD 11 Status REF
Premature ejaculation HA03.0Z Phase 1 [1]
Cross-matching ID
TTD ID
D0F2NF

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
5-HT 1A receptor (HTR1A) TTSQIFT 5HT1A_HUMAN Antagonist [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Premature ejaculation
ICD Disease Classification HA03.0Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
5-HT 1A receptor (HTR1A) DTT HTR1A 2.18E-01 -0.11 -0.51
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT00664365) FTIH Study With GSK958108. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of GlaxoSmithKline.