Details of the Drug

General Information of Drug (ID: DM5F0QY)

Drug Name
IONIS-416858
Synonyms IONIS-FXI-LRx
Indication
Disease Entry ICD 11 Status REF
Thrombosis DB61-GB90 Phase 2 [1]
Drug Type
Antisense oligonucleotide
Cross-matching ID
TTD ID
DD2C5E

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Factor XI messenger RNA (F11 mRNA) TTDM4ZU FA11_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Thrombosis
ICD Disease Classification DB61-GB90
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Factor XI messenger RNA (F11 mRNA) DTT F11 8.24E-01 -3.39E-03 -0.04
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Clinical pipeline report, company report or official report of Ionis Pharmaceuticals.