Details of the Drug

General Information of Drug (ID: DM5NC39)

Drug Name
SAGE-324
Indication
Disease Entry ICD 11 Status REF
Essential tremor or related tremors 8A04.1 Phase 2 [1]
Parkinson disease 8A00.0 Phase 1 [2]
Drug Type
Small molecular drug
Cross-matching ID
TTD ID
D4A2DQ
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
GABA(A) receptor (GABAR) TTCI43M NOUNIPROTAC Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT04305275) A Study to Evaluate the Efficacy, Safety, and Tolerability of SAGE-324 in Participants With Essential Tremor. U.S. National Institutes of Health.
2 Antibodies and venom peptides: new modalities for ion channels. Nat Rev Drug Discov. 2019 May;18(5):339-357.