Details of the Drug

General Information of Drug (ID: DM69UZG)

Drug Name

HPP-851

Synonyms

11-beta HSD-1 (metabolic disorders), High Point; 11-beta HSD-1 (metabolic disorders), TransTech Pharma; 11-beta hydroxysteroid dehydrogenase-1 inhibitors (metabolic disorders), Novo Nordisk; 11-beta hydroxysteroid dehydrogenase-1 inhibitors (metabolic disorders), TransTech Pharma

Indication

Disease Entry	ICD 11	Status	REF
Metabolic disorder	5C50-5D2Z	Preclinical	[1]
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Cross-matching ID

TTD ID: D0U1BU

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1)	TTN7BL9	DHI1_HUMAN	Inhibitor	[2]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease

Metabolic disorder

ICD Disease Classification

5C50-5D2Z

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1)	DTT	HSD11B1	2.03E-01	-0.01	-0.08

Molecular Expression Atlas (MEA)

MEA Detail

Jump to Detail Molecular Expression Atlas of This Drug

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027759)
2	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027759)