Details of the Drug

General Information of Drug (ID: DM7LVKP)

Drug Name

4-(furan-2-yl)thieno[3,2-d]pyrimidin-2-amine

Synonyms

CHEMBL406298; Thieno[3,2-d]pyrimidin-2-amine, 4-(2-furanyl)-; SCHEMBL3678073; ARPSUXKIHNZLQL-UHFFFAOYSA-N; BDBM50377489; 443148-30-9

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski): 0

Molecular Weight (mw)

217.25

Logarithm of the Partition Coefficient (xlogp)

1.7

Rotatable Bond Count (rotbonds)

1

Hydrogen Bond Donor Count (hbonddonor)

1

Hydrogen Bond Acceptor Count (hbondacc)

5

Chemical Identifiers

Formula: C10H7N3OS
IUPAC Name: 4-(furan-2-yl)thieno[3,2-d]pyrimidin-2-amine
Canonical SMILES: C1=COC(=C1)C2=NC(=NC3=C2SC=C3)N
InChI: InChI=1S/C10H7N3OS/c11-10-12-6-3-5-15-9(6)8(13-10)7-2-1-4-14-7/h1-5H,(H2,11,12,13)
InChIKey: ARPSUXKIHNZLQL-UHFFFAOYSA-N

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Adenosine A1 receptor (ADORA1)	TTK25J1	AA1R_HUMAN	Inhibitor	[1]
Adenosine A2a receptor (ADORA2A)	TTM2AOE	AA2AR_HUMAN	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Antagonists of the human adenosine A2A receptor. Part 3: Design and synthesis of pyrazolo[3,4-d]pyrimidines, pyrrolo[2,3-d]pyrimidines and 6-arylpu... Bioorg Med Chem Lett. 2008 May 1;18(9):2924-9.