Details of the Drug | DrugMAP

General Information of Drug (ID: DM8MYKL)

Drug Name

SR-1001

Synonyms

TH17 cell inhibitor (multiple sclerosis), Scripps

Indication

Disease Entry	ICD 11	Status	REF
Diabetic retinopathy	9B71.0	Preclinical	[1]
Multiple sclerosis	8A40	Investigative	[2]
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Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C15H13F6N3O4S2
Canonical SMILES: CC1=C(SC(=N1)NC(=O)C)S(=O)(=O)NC2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O
InChI: 1S/C15H13F6N3O4S2/c1-7-11(29-12(22-7)23-8(2)25)30(27,28)24-10-5-3-9(4-6-10)13(26,14(16,17)18)15(19,20)21/h3-6,24,26H,1-2H3,(H,22,23,25)
InChIKey: OZBSSKGBKHOLGA-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 44241473
TTD ID: D0O1WJ

Repurposed Drugs (RPD)

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References

1	RORt Inhibitor-SR1001 Halts Retinal Inflammation, Capillary Degeneration, and the Progression of Diabetic Retinopathy. Int J Mol Sci. 2020 May 17;21(10):3547.
2	The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.