Details of the Drug

General Information of Drug (ID: DM90VJ6)

Drug Name
6-Thiophen-3-yl-imidazo[2,1-b]thiazole
Synonyms 6-Thiophen-3-yl-imidazo[2,1-b]thiazole; 163851-59-0; CHEMBL273842; AKOS005145119
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 206.3
Logarithm of the Partition Coefficient (xlogp) 3.2
Rotatable Bond Count (rotbonds) 1
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C9H6N2S2
IUPAC Name
6-thiophen-3-ylimidazo[2,1-b][1,3]thiazole
Canonical SMILES
C1=CSC=C1C2=CN3C=CSC3=N2
InChI
InChI=1S/C9H6N2S2/c1-3-12-6-7(1)8-5-11-2-4-13-9(11)10-8/h1-6H
InChIKey
QNYBFCDYFVERKH-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
10352957
TTD ID
D07FRX

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
NADH dehydrogenase (MT-ND3) TTTJF7V NU3M_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Thienylimidazo[2,1-b]thiazoles as inhibitors of mitochondrial NADH dehydrogenase. J Med Chem. 1995 Mar 31;38(7):1090-7.