General Information of Drug (ID: DM90VJ6)

Drug Name
6-Thiophen-3-yl-imidazo[2,1-b]thiazole Drug Info
Synonyms 6-Thiophen-3-yl-imidazo[2,1-b]thiazole; 163851-59-0; CHEMBL273842; AKOS005145119
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
10352957
TTD Drug ID
DM90VJ6

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Investigative Drug(s)
Drug(s) Targeting NADH dehydrogenase (MT-ND3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
NADH DM5NM6E Parkinson disease 8A00.0 Approved [2]
N-Formylmethionine DM7GBDX Discovery agent N.A. Investigative [3]
6-Thiophen-2-yl-imidazo[2,1-b]thiazole DMC013U Discovery agent N.A. Investigative [1]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
NADH dehydrogenase (MT-ND3) TTTJF7V NU3M_HUMAN Inhibitor [1]

References

1 Thienylimidazo[2,1-b]thiazoles as inhibitors of mitochondrial NADH dehydrogenase. J Med Chem. 1995 Mar 31;38(7):1090-7.
2 Mechanism of cadmium-decreased glucuronidation in the rat. Biochem Pharmacol. 1992 Dec 1;44(11):2139-47.
3 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.