Details of the Drug

General Information of Drug (ID: DMAK3V7)

Drug Name

DIO-901

Synonyms

CAM-4044; VLD glucagon (diabetes), DiObex; Very low dose glucagon (diabetes), DiObex; VLD glucagon (FluidCrystal, diabetes), DiObex; VLD glucagon (extended-release, diabetes) DiObex

Indication

Disease Entry	ICD 11	Status	REF
Type-1 diabetes	5A10	Terminated	[1]
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Cross-matching ID

TTD ID: D0V3LD

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Glucagon receptor (GCGR)	TT9O6WS	GLR_HUMAN	Agonist	[2]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease

Type-1 diabetes

ICD Disease Classification

5A10

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Glucagon receptor (GCGR)	DTT	GCGR	7.24E-02	-0.52	-0.92

Molecular Expression Atlas (MEA)

MEA Detail

Jump to Detail Molecular Expression Atlas of This Drug

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022421)
2	Effects of low-dose and high-dose glucagon on glucose production and gluconeogenesis in humans. Metabolism. 2000 Jan;49(1):39-46.