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Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
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Clinical pipeline report, company report or official report of Lundbeck.
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URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4754).
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Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
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Multicenter, Randomized Trial of a Bionic Pancreas in Type 1 Diabetes. N Engl J Med. 2022 Sep 29;387(13):1161-1172.
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Pentoxifylline FDA Label
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ClinicalTrials.gov (NCT01359943) Efficacy, Safety and Tolerability of Secukinumab in Patients With Rheumatoid Arthritis Taking Methotrexate
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FDA Approved Drug Products from FDA Official Website. 2022. Application Number: 761183.
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NNZ-2566 treatment inhibits neuroinflammation and pro-inflammatory cytokine expression induced by experimental penetrating ballistic-like brain injury in rats. J Neuroinflammation. 2009 Aug 5;6:19.
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ClinicalTrials.gov (NCT00515632) Efficacy and Safety of Treatment With Balaglitazone in Type 2 Diabetes Patients on Stable Insulin Therapy. U.S. National Institutes of Health.
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| 11 |
ClinicalTrials.gov (NCT00751842) A Phase III Study to Investigate the Impact of Diamyd in Patients Newly Diagnosed With Type 1 Diabetes (USA)- DIAPREVENT. U.S. National Institutes of Health.
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| 12 |
ClinicalTrials.gov (NCT03791567) Islet Transplantation in Type I Diabetic Patients Using the University of Illinois at Chicago (UIC) Protocol. U.S. National Institutes of Health.
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URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2672).
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| 14 |
Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
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Efficacy and safety of itolizumab, a novel anti-CD6 monoclonal antibody, in patients with moderate to severe chronic plaque psoriasis: results of a double-blind, randomized, placebo-controlled, phase-III study. J Am Acad Dermatol. 2014 Sep;71(3):484-92.
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ClinicalTrials.gov (NCT01483898) An Efficacy and Safety Study of Ixmyelocel-T in Patients With Critical Limb Ischemia (CLI). U.S. National Institutes of Health.
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| 17 |
Clinical pipeline report, company report or official report of Novo Nordisk A/S.
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| 18 |
ClinicalTrials.gov (NCT00668850) Active Comparator Study of Generex Oral-lyn Spray and Injected Human Insulin. U.S. National Institutes of Health.
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| 19 |
ClinicalTrials.gov (NCT00411892) Effect of Inhaled Insulin (AERx iDMS) on Blood Glucose Control in Type 2 Diabetes. U.S. National Institutes of Health.
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| 20 |
The Hsp60 peptide p277 enhances anti-CD3 mediated diabetes remission in non-obese diabetic mice. J Autoimmun. 2015 May;59:61-6.
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URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2664).
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| 22 |
ClinicalTrials.gov (NCT01018173) A Study of Taspoglutide in Patients With Inadequately Controlled Diabetes Mellitus Type 2 and Cardiovascular Disease. U.S. National Institutes of Health.
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| 23 |
ClinicalTrials.gov (NCT00229710) GALLEX 9: Safety and Tolerability of Oral Tesaglitazar When Added to Insulin Therapy in Patients With Type 2 Diabetes. U.S. National Institutes of Health.
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| 24 |
ClinicalTrials.gov (NCT01686620) A Study Evaluating Safety and Efficacy of BIOD-123 Compared to Insulin Lispro (Humalog). U.S. National Institutes of Health.
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| 25 |
Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
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| 26 |
ClinicalTrials.gov (NCT04129528) Investigator- and Subject-blinded, Randomized, Placebo-controlled Study to Evaluate Safety, Tolerability, Pharmacokinetics and Efficacy Trial of CFZ533 in Pediatric and Young Adult Subjects With New Onset Type 1 Diabetes (T1DM). U.S.National Institutes of Health.
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| 27 |
Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034087)
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| 28 |
ClinicalTrials.gov (NCT00464555) Strategies to Improve Islet Survival. U.S. National Institutes of Health.
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| 29 |
URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8458).
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| 30 |
ClinicalTrials.gov (NCT03117998) Multiple Dose Study to Evaluate the Efficacy, Safety and Pharmacodynamics of REMD-477 in Subjects With Type 1 Diabetes Mellitus. U.S. National Institutes of Health.
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| 31 |
Clinical pipeline report, company report or official report of Tolerion.
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| 32 |
ClinicalTrials.gov (NCT00743002) A Trial of TT223 in Patients With Type 2 Diabetes Who Are Taking Metformin and/or Thiazolidinedione. U.S. National Institutes of Health.
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| 33 |
ClinicalTrials.gov (NCT03335371) Evaluation of TTP399 in Patients With Type 1 Diabetes (SimpliciT1). U.S. National Institutes of Health.
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| 34 |
ClinicalTrials.gov (NCT04956263) A Comparison of Postprandial Glucose After a Mixed Meal Tolerance Test, and the Metabolic Effects of Insulin Withdrawal in a Crossover Study of the Dual Systemic SGLT1 and SGLT2 Inhibitor YG1699, and the Selective SGLT2 Inhibitor Dapagliflozin in Subjects With Type 1 Diabetes. U.S.National Institutes of Health.
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| 35 |
ClinicalTrials.gov (NCT03751007) A Study to Assess the Safety and Tolerability of Different Doses of AG019 Administered Alone or in Combination With Teplizumab in Participants With Recently Diagnosed Type 1 Diabetes Mellitus (T1D). U.S. National Institutes of Health.
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| 36 |
ClinicalTrials.gov (NCT03895996) A Phase 1 / 2 Double-Blind, Randomized, Placebo Controlled Study of Safety, Tolerability and Potential Efficacy of AVOTRES Cell-Based Therapy (AVT001) in Patients With Type 1 Diabetes. U.S.National Institutes of Health.
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| 37 |
ClinicalTrials.gov (NCT00260234) Safety and Efficacy of PEG-Encapsulated Islet Allografts Implanted in Type I Diabetic Recipients. U.S. National Institutes of Health.
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| 38 |
Transplantation of Encapsulated Pancreatic Islets as a Treatment for Patients with Type 1 Diabetes Mellitus. Advances in Medicine. Volume 2014 (2014), Article ID 429710, 15 pages
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| 39 |
Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019847)
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| 40 |
ClinicalTrials.gov (NCT02239354) A Safety, Tolerability, and Efficacy Study of VC-01 Combination Product in Subjects With Type I Diabetes Mellitus
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| 41 |
ClinicalTrials.gov (NCT02193334) Phase I/II Study of KP-100IT in Acute Spinal Cord Injury. U.S. National Institutes of Health.
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| 42 |
ClinicalTrials.gov (NCT03163511) An Open-Label, First-In-Human Study Evaluating the Safety, Tolerability, and Efficacy of VC-02? Combination Product in Subjects With Type 1 Diabetes Mellitus and Hypoglycemia Unawareness. U.S.National Institutes of Health.
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| 43 |
ClinicalTrials.gov (NCT04678557) An Open-Label Phase 1/2 Study to Evaluate the Safety, Engraftment, and Efficacy of VC-01?Combination Product in Subjects With Type 1 Diabetes Mellitus [T1DM]. U.S.National Institutes of Health.
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| 44 |
ClinicalTrials.gov (NCT01053728) Study of How Single Rising Doses of SAR161271 Are Absorbed and Act in Patients With Type 1 Diabetes Mellitus (T1DM). U.S. National Institutes of Health.
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| 45 |
ClinicalTrials.gov (NCT04786262) A Phase 1/2 Study to Evaluate the Safety, Tolerability, and Efficacy of VX-880 in Subjects Who Have Type 1 Diabetes Mellitus With Impaired Hypoglycemic Awareness and Severe Hypoglycemia. U.S.National Institutes of Health.
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| 46 |
ClinicalTrials.gov (NCT00453375) Phase 1 Study of BHT-3021 in Subjects With Type 1 Diabetes Mellitus. U.S. National Institutes of Health.
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| 47 |
Clinical pipeline report, company report or official report of Boston Therapeutics.
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| 48 |
ClinicalTrials.gov (NCT00057499) Evaluation of a Diabetes Vaccine in Newly Diagnosed Diabetics. U.S. National Institutes of Health.
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| 49 |
ClinicalTrials.gov (NCT04625595) A Phase 1b, Randomized, Single-blind, Placebo-controlled, Multiple Ascending Dose (MAD) Study to Assess the Steady-State Pharmacokinetics and DQ8 Blocking Efficacy of Orally Administered IMT-002 in Patients With Type 1 Diabetes and HLA-DQ8. U.S.National Institutes of Health.
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Prevention of Type 1 Diabetes Mellitus using a Novel Vaccine. Ther Adv Endocrinol Metab. 2011 February; 2(1): 9-16.
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| 51 |
Clinical pipeline report, company report or official report of Biodel.
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ClinicalTrials.gov (NCT03170544) Single Ascending Dose Study of MK-1092 in Healthy Participants and in Participants With Type 1 and Type 2 Diabetes Mellitus (MK-1092-001). U.S. National Institutes of Health.
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| 53 |
ClinicalTrials.gov (NCT02528799) Safety and Tolerability of Nexvax2 in Subjects With Celiac Disease.
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| 54 |
ClinicalTrials.gov (NCT00400283) A Study Looking Into the Effect of NNC 55-0414 in Subjects With Type 2 Diabetes. U.S. National Institutes of Health.
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| 55 |
Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800037233)
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| 56 |
Alize Pharma announces positive results for AZP-531, its unacylated ghrelin analog, from two Phase I clinical trials in healthy volunteers and obese subjects. Lyon, France, December 10, 2014.
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| 57 |
ClinicalTrials.gov (NCT05210530) An Open-Label, First-In-Human Study Evaluating the Safety and Tolerability of VCTX210A Combination Product in Subjects With Type 1 Diabetes Mellitus (T1D). U.S.National Institutes of Health.
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URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2687).
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Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011739)
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Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015896)
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Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011773)
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Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010082)
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Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016001)
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Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022421)
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Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015749)
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The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
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Alterations of ADAMTSs and TIMP-3 in human nucleus pulposus cells subjected to compressive load: Implications in the pathogenesis of human intervertebral disc degeneration.J Orthop Res. 2012 Feb;30(2):267-73. doi: 10.1002/jor.21507. Epub 2011 Aug 1.
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Leptin downregulates aggrecan through the p38-ADAMST pathway in human nucleus pulposus cells.PLoS One. 2014 Oct 9;9(10):e109595. doi: 10.1371/journal.pone.0109595. eCollection 2014.
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Type 1 diabetes in mice and men: gene expression profiling to investigate disease pathogenesis.Immunol Res. 2014 May;58(2-3):340-50. doi: 10.1007/s12026-014-8501-8.
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Enhanced A2A adenosine receptor-mediated increase in coronary flow in type I diabetic mice.J Mol Cell Cardiol. 2016 Jan;90:30-7. doi: 10.1016/j.yjmcc.2015.11.033. Epub 2015 Dec 2.
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The insulin-melatonin antagonism: studies in the LEW.1AR1-iddm rat (an animal model of human type 1 diabetes mellitus).Diabetologia. 2011 Jul;54(7):1831-40. doi: 10.1007/s00125-011-2138-0. Epub 2011 Apr 15.
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Dietary advanced glycated end-products and medicines influence the expression of SIRT1 and DDOST in peripheral mononuclear cells from long-term type 1 diabetes patients.Diab Vasc Dis Res. 2018 Jan;15(1):81-89. doi: 10.1177/1479164117733918. Epub 2017 Oct 13.
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Microvascular vasodilator properties of the angiotensin II type 2 receptor in a mouse model of type 1 diabetes.Sci Rep. 2017 Mar 31;7:45625. doi: 10.1038/srep45625.
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Increased Indoleamine 2,3-Dioxygenase and Quinolinic Acid Expression in Microglia and Mller Cells of Diabetic Human and Rodent Retina.Invest Ophthalmol Vis Sci. 2017 Oct 1;58(12):5043-5055. doi: 10.1167/iovs.17-21654.
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The Four-Way Stop Sign: Viruses, 12-Lipoxygenase, Islets, and Natural Killer Cells in Type 1 Diabetes Progression.Front Endocrinol (Lausanne). 2017 Sep 25;8:246. doi: 10.3389/fendo.2017.00246. eCollection 2017.
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Amylase alpha-2A autoantibodies: novel marker of autoimmune pancreatitis and fulminant type 1 diabetes.Diabetes. 2009 Mar;58(3):732-7. doi: 10.2337/db08-0493. Epub 2008 Nov 10.
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Association between plasma activities of semicarbazide-sensitive amine oxidase and angiotensin-converting enzyme in patients with type 1 diabetes mellitus.Diabetologia. 2005 May;48(5):1002-7. doi: 10.1007/s00125-005-1716-4. Epub 2005 Apr 14.
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The apolipoprotein A-IV Gln360His polymorphism predicts progression of coronary artery calcification in patients with type 1 diabetes.Diabetologia. 2006 Aug;49(8):1946-54. doi: 10.1007/s00125-006-0317-1. Epub 2006 Jun 13.
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Is APOC3 the driver of cardiovascular disease in people with type I diabetes mellitus?.J Clin Invest. 2019 Oct 1;129(10):4074-4076. doi: 10.1172/JCI131333.
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Molecular mechanism of the increased tissue uptake of trivalent inorganic arsenic in mice with type 1 diabetes mellitus.Biochem Biophys Res Commun. 2018 Oct 2;504(2):393-399. doi: 10.1016/j.bbrc.2018.06.029. Epub 2018 Jun 19.
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Inhibition of Rho kinase protects from ischaemia-reperfusion injury via regulation of arginase activity and nitric oxide synthase in type 1 diabetes.Diab Vasc Dis Res. 2017 May;14(3):236-245. doi: 10.1177/1479164116687935. Epub 2017 Feb 9.
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Downregulation of microRNA-125a is involved in intervertebral disc degeneration by targeting pro-apoptotic Bcl-2 antagonist killer 1.Iran J Basic Med Sci. 2017 Nov;20(11):1260-1267. doi: 10.22038/IJBMS.2017.9542.
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Evaluation of 19 autoimmune disease-associated loci with rheumatoid arthritis in a Colombian population: evidence for replication and gene-gene interaction.J Rheumatol. 2011 Sep;38(9):1866-70. doi: 10.3899/jrheum.110199. Epub 2011 Jul 15.
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Association study between B- and T-lymphocyte attenuator gene and type 1 diabetes mellitus or systemic lupus erythematosus in the Japanese population.Int J Immunogenet. 2009 Feb;36(1):65-8. doi: 10.1111/j.1744-313X.2008.00809.x.
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Down-regulation of islet amyloid polypeptide expression induces death of human annulus fibrosus cells via mitochondrial and death receptor pathways.Biochim Biophys Acta Mol Basis Dis. 2017 Jun;1863(6):1479-1491. doi: 10.1016/j.bbadis.2017.04.016. Epub 2017 Apr 19.
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Fas/FasL-mediated cell death in rat's diabetic hearts involves activation of calcineurin/NFAT4 and is potentiated by a high-fat diet rich in corn oil.J Nutr Biochem. 2019 Jun;68:79-90. doi: 10.1016/j.jnutbio.2019.03.007. Epub 2019 Mar 28.
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Evidence of a functional role for mast cells in the development of type 1 diabetes mellitus in the BioBreeding rat.J Immunol. 2006 Nov 15;177(10):7275-86. doi: 10.4049/jimmunol.177.10.7275.
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Fine mapping of a region on chromosome 21q21.11-q22.3 showing linkage to type 1 diabetes.J Med Genet. 2005 Jan;42(1):17-25. doi: 10.1136/jmg.2004.022004.
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Prevention and treatment of diabetes with resveratrol in a non-obese mouse model of type 1 diabetes.Diabetologia. 2011 May;54(5):1136-46. doi: 10.1007/s00125-011-2064-1. Epub 2011 Feb 22.
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DC-SIGN polymorphisms are associated to type 1 diabetes mellitus.Immunobiology. 2014 Nov;219(11):859-65. doi: 10.1016/j.imbio.2014.07.011. Epub 2014 Jul 22.
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Soluble B7-H3 (sB7-H3) is over-expressed in the serum of type 1 diabetes patients.Diabetes Res Clin Pract. 2018 Sep;143:332-336. doi: 10.1016/j.diabres.2018.08.004. Epub 2018 Aug 4.
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Possible association of the CD4 gene polymorphism with vitiligo in an Iranian population.Clin Exp Dermatol. 2010 Jul;35(5):521-4. doi: 10.1111/j.1365-2230.2009.03667.x. Epub 2009 Oct 19.
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T cell regulation mediated by interaction of soluble CD52 with the inhibitory receptor Siglec-10.Nat Immunol. 2013 Jul;14(7):741-8. doi: 10.1038/ni.2610. Epub 2013 May 19.
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Type 1 diabetes: Developing the first risk-estimation model for predicting silent myocardial ischemia. The potential role of insulin resistance.PLoS One. 2017 Apr 3;12(4):e0174640. doi: 10.1371/journal.pone.0174640. eCollection 2017.
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Risk of type 1 diabetes in childhood and maternal age at delivery, interaction with ACP1 and sex.Diabetes Metab Res Rev. 2005 Jul-Aug;21(4):353-8. doi: 10.1002/dmrr.521.
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Impaired processing and presentation by MHC class II proteins in human diabetic cells.J Immunol. 2003 Jan 1;170(1):620-7. doi: 10.4049/jimmunol.170.1.620.
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High-density lipoprotein cholesterol is related to the TaqIB cholesteryl ester transfer protein gene polymorphism and smoking, but not to moderate alcohol consumption in insulin-dependent diabetic men.Scand J Clin Lab Invest. 1998 May;58(3):251-8. doi: 10.1080/00365519850186643.
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Increase of cardiac M2-muscarinic receptor gene expression in type-1 but not in type-2 diabetic rats.Neurosci Lett. 2008 Aug 22;441(2):201-4. doi: 10.1016/j.neulet.2008.06.003. Epub 2008 Jun 5.
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Endurance training reverts heart mitochondrial dysfunction, permeability transition and apoptotic signaling in long-term severe hyperglycemia.Mitochondrion. 2011 Jan;11(1):54-63. doi: 10.1016/j.mito.2010.07.005. Epub 2010 Jul 21.
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Aerobic exercise training decreases cereblon and increases AMPK signaling in the skeletal muscle of STZ-induced diabetic rats.Biochem Biophys Res Commun. 2018 Jun 22;501(2):448-453. doi: 10.1016/j.bbrc.2018.05.009. Epub 2018 May 10.
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Targeted Deep Sequencing in Multiple-Affected Sibships of European Ancestry Identifies Rare Deleterious Variants in PTPN22 That Confer Risk for Type 1 Diabetes.Diabetes. 2016 Mar;65(3):794-802. doi: 10.2337/db15-0322. Epub 2015 Dec 2.
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Downregulation of cathepsin G reduces the activation of CD4+ T cells in murine autoimmune diabetes.Am J Transl Res. 2017 Nov 15;9(11):5127-5137. eCollection 2017.
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Integration of disease association and eQTL data using a Bayesian colocalisation approach highlights six candidate causal genes in immune-mediated diseases.Hum Mol Genet. 2015 Jun 15;24(12):3305-13. doi: 10.1093/hmg/ddv077. Epub 2015 Mar 5.
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Polymorphisms in the cathepsin L2 (CTSL2) gene show association with type 1 diabetes and early-onset myasthenia gravis.Hum Immunol. 2007 Sep;68(9):748-55. doi: 10.1016/j.humimm.2007.05.009. Epub 2007 Jun 28.
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The role of cubilin gene polymorphisms and their influence on 25(OH)D3 and 1,25(OH)2D3 plasma levels in type 1 diabetes patients.J Steroid Biochem Mol Biol. 2010 Jul;121(1-2):442-4. doi: 10.1016/j.jsbmb.2010.03.087. Epub 2010 Apr 14.
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Eukaryotic translation initiation factor 5A inhibition alters physiopathology and immune responses in a "humanized" transgenic mouse model of type 1 diabetes.Am J Physiol Endocrinol Metab. 2014 Apr 1;306(7):E791-8. doi: 10.1152/ajpendo.00537.2013. Epub 2014 Feb 4.
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Blunting of the immediate-early gene and mitogenic response in hepatectomized type 1 diabetic animals.Am J Physiol. 1995 Oct;269(4 Pt 1):E691-700. doi: 10.1152/ajpendo.1995.269.4.E691.
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E2f1 mutation induces early onset of diabetes and Sjgren's syndrome in nonobese diabetic mice.J Immunol. 2004 Oct 15;173(8):4908-18. doi: 10.4049/jimmunol.173.8.4908.
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The Association between rs2292239 Polymorphism in ERBB3 Gene and Type 1 Diabetes: A Meta-Analysis.Biomed Res Int. 2019 Aug 6;2019:7689642. doi: 10.1155/2019/7689642. eCollection 2019.
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Targeting ABL-IRE1 Signaling Spares ER-Stressed Pancreatic Cells to Reverse Autoimmune Diabetes.Cell Metab. 2017 Apr 4;25(4):883-897.e8. doi: 10.1016/j.cmet.2017.03.018.
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Urinary liver-type fatty acid binding protein is an independent predictor of stroke and mortality in individuals with type 1 diabetes.Diabetologia. 2017 Sep;60(9):1782-1790. doi: 10.1007/s00125-017-4328-x. Epub 2017 Jun 10.
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Materno-Fetal Transfer of Preproinsulin Through the Neonatal Fc Receptor Prevents Autoimmune Diabetes.Diabetes. 2015 Oct;64(10):3532-42. doi: 10.2337/db15-0024. Epub 2015 Apr 27.
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Free fatty acid receptor 2, a candidate target for type 1 diabetes, induces cell apoptosis through ERK signaling.J Mol Endocrinol. 2014 Dec;53(3):367-80. doi: 10.1530/JME-14-0065. Epub 2014 Oct 8.
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FGF21 and glycemic control in patients with T1D.Endocrine. 2019 Sep;65(3):550-557. doi: 10.1007/s12020-019-02027-3. Epub 2019 Aug 1.
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Bioinformatics analysis of gene expression in peripheral blood mononuclear cells from children with type 1 diabetes in 3 periods.Exp Clin Endocrinol Diabetes. 2014 Sep;122(8):477-83. doi: 10.1055/s-0034-1372599. Epub 2014 May 16.
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A method for gene-based pathway analysis using genomewide association study summary statistics reveals nine new type 1 diabetes associations.Genet Epidemiol. 2014 Dec;38(8):661-70. doi: 10.1002/gepi.21853. Epub 2014 Nov 4.
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Capsaicin Reduces Blood Glucose by Increasing Insulin Levels and Glycogen Content Better than Capsiate in Streptozotocin-Induced Diabetic Rats.J Agric Food Chem. 2017 Mar 22;65(11):2323-2330. doi: 10.1021/acs.jafc.7b00132. Epub 2017 Mar 2.
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Detection and Characterization of CD8(+) Autoreactive Memory Stem T Cells in Patients With Type 1 Diabetes.Diabetes. 2018 May;67(5):936-945. doi: 10.2337/db17-1390. Epub 2018 Mar 5.
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Efficacy of Growth Hormone Treatment in Children with Type 1 Diabetes Mellitus and Growth Hormone Deficiency-An Analysis of KIGS Data.J Pediatr. 2018 Jul;198:260-264. doi: 10.1016/j.jpeds.2018.02.035. Epub 2018 Apr 12.
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Associations of serum glucagon levels with glycemic variability in type 1 diabetes with different disease durations.Endocrine. 2018 Sep;61(3):473-481. doi: 10.1007/s12020-018-1641-1. Epub 2018 Jun 18.
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Statistical colocalization of monocyte gene expression and genetic risk variants for type 1 diabetes.Hum Mol Genet. 2012 Jun 15;21(12):2815-24. doi: 10.1093/hmg/dds098. Epub 2012 Mar 8.
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Screening for Type 1 Diabetes Risk in Newborns: The Freder1k Pilot Study in Saxony.Horm Metab Res. 2018 Jan;50(1):44-49. doi: 10.1055/s-0043-120921. Epub 2017 Nov 9.
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HMGCS2 is a key ketogenic enzyme potentially involved in type 1 diabetes with high cardiovascular risk.Sci Rep. 2017 Jul 4;7(1):4590. doi: 10.1038/s41598-017-04469-z.
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HSP 10 is a new autoantigen in both autoimmune pancreatitis and fulminant type 1 diabetes.Biochem Biophys Res Commun. 2009 Aug 14;386(1):192-6. doi: 10.1016/j.bbrc.2009.06.009. Epub 2009 Jun 9.
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HTR1A a novel type 1 diabetes susceptibility gene on chromosome 5p13-q13.PLoS One. 2012;7(5):e35439. doi: 10.1371/journal.pone.0035439. Epub 2012 May 1.
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The dual role of autoimmune regulator in maintaining normal expression level of tissue-restricted autoantigen in the thymus: A modeling investigation.Math Biosci. 2017 May;287:12-23. doi: 10.1016/j.mbs.2016.10.002. Epub 2016 Oct 17.
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IFN-gamma affects homing of diabetogenic T cells.J Immunol. 2001 Dec 1;167(11):6637-43. doi: 10.4049/jimmunol.167.11.6637.
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Polymorphism discovery and association analyses of the interferon genes in type 1 diabetes.BMC Genet. 2006 Feb 22;7:12. doi: 10.1186/1471-2156-7-12.
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VSEAMS: a pipeline for variant set enrichment analysis using summary GWAS data identifies IKZF3, BATF and ESRRA as key transcription factors in type 1 diabetes.Bioinformatics. 2014 Dec 1;30(23):3342-8. doi: 10.1093/bioinformatics/btu571. Epub 2014 Aug 27.
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