Details of the Drug

General Information of Drug (ID: DMAN21O)

Drug Name
VG-101
Synonyms Seala; VG-101 analogs, Bionovo; Estrogen receptor beta selective agonists (topical intravaginal gel, vaginal dryness), Bionovo; VG-101 (topical intravaginal gel, vaginal dryness), Bionovo
Indication
Disease Entry ICD 11 Status REF
Menopause symptom GA30.0 Phase 1/2 [1]
Cross-matching ID
TTD ID
D01PTS

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Estrogen receptor beta (ESR2) TTOM3J0 ESR2_HUMAN Agonist [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Menopause symptom
ICD Disease Classification GA30.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Estrogen receptor beta (ESR2) DTT ESR2 2.09E-01 -0.06 -0.17
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT00453089) VG101 Phase I/II to Treat Vulvar and Vaginal Atrophy in Post-Menopausal Women. U.S. National Institutes of Health.
2 Update on alternative therapies for vulvovaginal atrophy. Patient Prefer Adherence. 2011; 5: 533-536.