Details of Disease

General Information of Disease (ID: DISQ562P)

• Disease Name: Menopause symptom
• Disease Class: GA30: Menopausal disorder
• Disease Hierarchy:
  DIS01GPL: Grass pollen hypersensitivity
  DISQ562P: Menopause symptom
• ICD Code:
  ICD-11: ICD-11: GA30.0
  Expand ICD-10: F30,F31,F32,F33,F34,F35,F36,F37,F38,F39,F32,F33,N95
  Expand ICD-9: 296,296.2,296.3,627.2

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 4 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Cenestin	DMXQS7K	Approved	Small molecular drug	[1]
Conjugated Estrogens	DMLT0E1	Approved	Small molecular drug	[2]
Desvenlafaxine	DMHD4PE	Approved	Small molecular drug	[3]
Estrogen	DMGY0UT	Approved	NA	[1]

This Disease is Treated as An Indication in 2 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Genistein	DM0JETC	Phase 2/3	Small molecular drug	[4]
VG-101	DMAN21O	Phase 1/2	NA	[5]

This Disease is Treated as An Indication in 1 Discontinued Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Chlorotrianisene	DMSV2WZ	Withdrawn from market	Small molecular drug	[6]

This Disease is Treated as An Indication in 1 Investigative Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
TSERaM	DM6JF7T	Investigative	NA	[7]

Molecular Interaction Atlas (MIA) of This Disease

References

• [1] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
• [2] ClinicalTrials.gov (NCT01613170) Premarin Versus Toviaz for Treatment of Overactive Bladder. U.S. National Institutes of Health.
• [3] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7158).
• [4] ClinicalTrials.gov (NCT00355953) Vascular and Skeletal Protective Effects of Genistein in Postmenopausal Women. U.S. National Institutes of Health.
• [5] ClinicalTrials.gov (NCT00453089) VG101 Phase I/II to Treat Vulvar and Vaginal Atrophy in Post-Menopausal Women. U.S. National Institutes of Health.
• [6] FDA Approved Drug Products from FDA Official Website. 2008. Application Number: (ANDA) 017675.
• [7] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 620).