Details of the Drug

General Information of Drug (ID: DMDKTYU)

Drug Name
Anti-EGFRvIII CAR transduced PBL
Indication
Disease Entry ICD 11 Status REF
Brain cancer 2A00 Phase 1/2 [1]
Malignant glioma 2A00.0 Phase 1/2 [1]
Recurrent glioblastoma 2A00.00 Phase 1/2 [1]
Drug Type
CAR T Cell Therapy
Cross-matching ID
TTD ID
D08RJY

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Epidermal growth factor receptor variant III (EGFR vIII) TTZ6B2I EGFR_HUMAN CAR-T-Cell-Therapy [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT01454596) CAR T Cell Receptor Immunotherapy Targeting EGFRvIII for Patients With Malignant Gliomas Expressing EGFRvIII. U.S. National Institutes of Health.