Details of the Drug

General Information of Drug (ID: DMLEPYN)

Drug Name

Tetramethylammonium Ion

Synonyms

Tetramethylammonium; TETRAMETHYLAMMONIUM ION; tetramethylazanium; 51-92-3; N,N,N-trimethylmethanaminium; UNII-H0W55235FC; Tetramethylammonium octahydrotriborate; EINECS 235-626-5; CHEMBL46486; Methanaminium, N,N,N-trimethyl-, octahydrotriborate(1-); CHEBI:46020; Methanaminium, N,N,N-trimethyl-; H0W55235FC; Tetramethylammonium pentaiodide; Tetramethyl-Ammonium; Ammonium, (pentaiodide); AC1L1MEF; 19269-48-8; bmse000780; 64-20-0 (bromide); 75-59-2 (hydroxide); 75-57-0 (chloride); 75-58-1 (iodide); 12386-10-6; 373-68-2 (fluoride)

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski): 0

Molecular Weight (mw)

74.14

Logarithm of the Partition Coefficient (xlogp)

0.3

Rotatable Bond Count (rotbonds)

Hydrogen Bond Donor Count (hbonddonor)

Hydrogen Bond Acceptor Count (hbondacc)

Chemical Identifiers

Formula: C4H12N+
IUPAC Name: tetramethylazanium
Canonical SMILES: C[N+](C)(C)C
InChI: InChI=1S/C4H12N/c1-5(2,3)4/h1-4H3/q+1
InChIKey: QEMXHQIAXOOASZ-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 6380
ChEBI ID: CHEBI:46020
CAS Number: 51-92-3
DrugBank ID: DB03095
TTD ID: D0T9SK
VARIDT ID: DR01474

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
UDP-glucose 4-epimerase (GALE)	TTGRHIB	GALE_HUMAN	Inhibitor	[1]

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Drug Transporter (DTP)

DTP Name	DTP ID	UniProt ID	MOA	REF
Organic cation transporter 1 (SLC22A1)	DTT79CX	S22A1_HUMAN	Substrate	[2]

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Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Cholinesterase (BCHE)	OTOH3WQ9	CHLE_HUMAN	Gene/Protein Processing	[3]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
2	Scintillation proximity assay for measuring uptake by the human drug transporters hOCT1, hOAT3, and hOATP1B1. Anal Biochem. 2007 Jul 15;366(2):117-25.
3	The mechanism and benefit of human butyrylcholinesterase activation by what would otherwise be inhibitors. Chem Biol Interact. 2019 Aug 1;308:350-356.