Details of the Drug

General Information of Drug (ID: DMQ6KZM)

Drug Name
ABI-009
Indication
Disease Entry ICD 11 Status REF
Malignant perivascular epithelioid cell tumour 2B5Y Phase 2 [1]
Solid tumour/cancer 2A00-2F9Z Phase 2 [2]
Non-muscle invasive bladder cancer 2C94 Phase 1/2 [1]
Pulmonary arterial hypertension BB01.0 Phase 1 [3]
Cross-matching ID
TTD ID
D0W3UV
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Serine/threonine-protein kinase mTOR (mTOR) TTCJG29 MTOR_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Malignant perivascular epithelioid cell tumour
ICD Disease Classification 2B5Y
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Serine/threonine-protein kinase mTOR (mTOR) DTT MTOR 2.16E-05 -0.44 -2.3
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 ClinicalTrials.gov (NCT02494570) A Phase 2 Study of ABI-009 in Patients With Advanced Malignant PEComa.
3 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)