Details of the Drug

General Information of Drug (ID: DMRBZ3X)

Drug Name
[14C]methylamine
Synonyms [14C]-methylamine
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 33.05
Logarithm of the Partition Coefficient (xlogp) -0.7
Rotatable Bond Count (rotbonds) 0
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 1
Chemical Identifiers
Formula
CH5N
IUPAC Name
(114C)methanamine
Canonical SMILES
[14CH3]N
InChI
InChI=1S/CH5N/c1-2/h2H2,1H3/i1+2
InChIKey
BAVYZALUXZFZLV-NJFSPNSNSA-N
Cross-matching ID
PubChem CID
190331
TTD ID
D0JS4B
VARIDT ID
DR01137

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Ammonium transporter Rh type A (RHAG) TTVHFE8 RHAG_HUMAN Modulator [2]
Ammonium transporter Rh type C (RHCG) TTN5MZ3 RHCG_HUMAN Modulator [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4624).
2 The Rh complex exports ammonium from human red blood cells. Br J Haematol. 2003 Jul;122(2):333-40.
3 Characterization of ammonia transport by the kidney Rh glycoproteins RhBG and RhCG. Am J Physiol Renal Physiol. 2006 Feb;290(2):F297-305.