Details of the Drug

General Information of Drug (ID: DMRHJOO)

Drug Name

SY-2101

Indication

Disease Entry	ICD 11	Status	REF
Acute promyelocytic leukaemia	2A60.0	Phase 1	[1]
------------------------------------------------------------------------------------

Drug Type

Small molecule

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
F-box-like/WD repeat-containing protein TBL1X (TBL1X)	TTAL6S1	TBL1X_HUMAN	Not Available	[2]

------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT04996030) An Open-label Phase 1 Study to Evaluate Pharmacokinetics, Safety, and Tolerability of SY-2101 in Adult Patients With Acute Promyelocytic Leukemia. U.S.National Institutes of Health.
2	Transducin beta-like protein 1 controls multiple oncogenic networks in diffuse large B-cell lymphoma. Haematologica. 2021 Nov 1;106(11):2927-2939.