Details of the Drug

General Information of Drug (ID: DMRQOXG)

Drug Name
Etrabamine
Synonyms 14839-JL
Indication
Disease Entry ICD 11 Status REF
Parkinson disease 8A00.0 Terminated [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 168.26
Logarithm of the Partition Coefficient (xlogp) 1.3
Rotatable Bond Count (rotbonds) 1
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C8H12N2S
IUPAC Name
N-methyl-4,5,6,7-tetrahydro-1,3-benzothiazol-6-amine
Canonical SMILES
CNC1CCC2=C(C1)SC=N2
InChI
InChI=1S/C8H12N2S/c1-9-6-2-3-7-8(4-6)11-5-10-7/h5-6,9H,2-4H2,1H3
InChIKey
YDSVAKPJAOSZJA-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
68895
CAS Number
70590-58-8
TTD ID
D0LS4U

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Dopamine D2 receptor (D2R) TTEX248 DRD2_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Parkinson disease
ICD Disease Classification 8A00.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Dopamine D2 receptor (D2R) DTT DRD2 2.50E-02 -0.08 -0.49
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003368)
2 WO patent application no. 2009,0568,11, Medicaments.