Details of the Drug

General Information of Drug (ID: DMRZMKT)

Drug Name
AP-1189
Synonyms AP-1089; Melanocortin receptor-1 modulator (oral, inflammation), Action Pharma
Indication
Disease Entry ICD 11 Status REF
Atopic dermatitis EA80 Investigative [1]
Cross-matching ID
PubChem CID
23728926
TTD ID
D09QPE

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Melanocortin receptor 1 (MC1R) TT0MV2T MSHR_HUMAN Modulator [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

ICD Disease Classification 14 Disease of the skin
Disease Class ICD-11: EA90 Psoriasis
The Studied Tissue Skin
The Studied Disease Atopic dermatitis [ICD-11:EA90]
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Melanocortin receptor 1 (MC1R) DTT MC1R 1.44E-06 0.41 2.15
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 282).