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FDA Approved Drug Products from FDA Official Website. 2023. Application Number: 213871.
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Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
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URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5171).
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2016 FDA drug approvals. Nat Rev Drug Discov. 2017 Feb 2;16(2):73-76.
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ClinicalTrials.gov (NCT00745199) Evaluating the Effect of Cromolyn Sodium in Uremic Pruritus. U.S. National Institutes of Health.
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URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7066).
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2017 FDA drug approvals.Nat Rev Drug Discov. 2018 Feb;17(2):81-85.
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URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6783).
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Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
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URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6962).
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ClinicalTrials.gov (NCT01359943) Efficacy, Safety and Tolerability of Secukinumab in Patients With Rheumatoid Arthritis Taking Methotrexate
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ClinicalTrials.gov (NCT02564042) A Dose-Finding Study of GSK2894512 Cream in Subjects With Plaque Psoriasis.
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FDA Approved Drug Products from FDA Official Website. 2021. Application Number: 761180.
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ClinicalTrials.gov (NCT04804605) Open Label Extension Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic Dermatitis (INTEGUMENT-OLE). U.S. National Institutes of Health.
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ClinicalTrials.gov (NCT05614817) A Randomized, Double-blind, Placebo-controlled Phase 3 Trial to Evaluate the Efficacy and Safety of CBP-201 Monotherapy in Patients With Moderate-To-Severe Atopic Dermatitis Who Are Candidates for Systemic Therapy. U.S.National Institutes of Health.
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ClinicalTrials.gov (NCT03989206) Long-term Safety and Efficacy of Nemolizumab With Moderate-to-severe Atopic Dermatitis. U.S. National Institutes of Health.
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ClinicalTrials.gov (NCT05633355) A Phase 3, Open-label, 52-week Study to Assess the Safety, Tolerability, and Efficacy of Rocatinlimab (AMG 451) in Adolescent Subjects Aged >= 12 to < 18 Years With Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-Orbit). U.S.National Institutes of Health.
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ClinicalTrials.gov (NCT02134028) Long-Term Safety Evaluation of Dupilumab in Patients With Asthma. U.S. National Institutes of Health.
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Emerging drugs for asthma. Expert Opin Emerg Drugs. 2008 Dec;13(4):643-53.
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ClinicalTrials.gov (NCT05509023) A Randomized, Double-Blind, Placebo-Controlled Phase 2a Proof-of-Concept Study Evaluating the Safety and Efficacy of ADX-914 in Subjects With Moderate to Severe Atopic Dermatitis. U.S.National Institutes of Health.
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OX40-OX40L Inhibition for the Treatment of Atopic Dermatitis-Focus on Rocatinlimab and Amlitelimab. Pharmaceutics. 2022 Dec 8;14(12):2753.
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ClinicalTrials.gov (NCT01301508) Efficacy and Safety of AN2898 and AN2728 Topical Ointments to Treat Mild-to-Moderate Atopic Dermatitis. U.S. National Institutes of Health.
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Clinical pipeline report, company report or official report of Anacor Pharmaceuticals.
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ClinicalTrials.gov (NCT01756898) A Study to Evaluate the Efficacy, Safety and Pharmacokinetics of ASB17061 Capsules in Adult Subjects With Atopic Dermatitis. U.S. National Institutes of Health.
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ClinicalTrials.gov (NCT03759340) ATI-502 Topical Solution for the Treatment of Alopecia Areata (AA), Alopecia Universalis (AU) and Alopecia Totalis (AT). U.S. National Institutes of Health.
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ClinicalTrials.gov (NCT00883311) A Study of BRT-FC-83C for the Treatment of Atopic Dermatitis. U.S. National Institutes of Health.
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Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024035)
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ClinicalTrials.gov (NCT01447017) A Study of DPK-060 to Investigate Clinical Safety and Efficacy in Patients With Acute External Otitis. U.S. National Institutes of Health.
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29 |
ClinicalTrials.gov (NCT01461941) A Phase 2 Study of E6005 in Patients With Atopic Dermatitis. U.S. National Institutes of Health.
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30 |
ClinicalTrials.gov (NCT01299610) A Study to Test the Effect of 2 Different Doses of Topical GW870086X on Atopic Dermatitis Also Including a Postive Control and a Placebo. U.S. National Institutes of Health.
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31 |
ClinicalTrials.gov (NCT01568489) Phase 2 Study of HL-009 Liposomal Gel to Treat Mild to Moderate Atopic Dermatitis. U.S. National Institutes of Health.
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32 |
ClinicalTrials.gov (NCT00455429) An Efficacy and Safety Study of JNJ-26113100 in the Treatment of Adult Atopic Dermatitis. U.S. National Institutes of Health.
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33 |
ClinicalTrials.gov (NCT01067833) Phase 2 Study of Oral K201 for Prevention of AF Recurrence. U.S. National Institutes of Health.
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34 |
ClinicalTrials.gov (NCT01119339) Study to Investigate Dose-related Efficacy of LAS41004 in the Treatment of Psoriasis. U.S. National Institutes of Health.
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35 |
ClinicalTrials.gov (NCT01037881) LEO 29102 Cream in the Treatment of Atopic Dermatitis. U.S. National Institutes of Health.
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36 |
Clinical pipeline report, company report or official report of NicOx SA.
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37 |
ClinicalTrials.gov (NCT02052531) Efficacy and Safety Study of PAC-14028 Cream in Dermal Pruritus. U.S. National Institutes of Health.
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38 |
ClinicalTrials.gov (NCT05375955) A PHASE 2B, RANDOMIZED, DOUBLE BLIND, VEHICLE CONTROLLED, PARALLEL GROUP STUDY TO ASSESS THE EFFICACY, SAFETY, TOLERABILITY AND PHARMACOKINETICS OF MULTIPLE DOSE LEVELS OF PF-07038124 OINTMENT FOR 12 WEEKS IN PARTICIPANTS 12 YEARS AND OLDER AND WITH MILD-TO-MODERATE ATOPIC DERMATITIS OR MILD-TO-SEVERE PLAQUE PSORIASIS. U.S.National Institutes of Health.
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URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 579).
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ClinicalTrials.gov (NCT03571620) Safety and Efficacy Study of Q301 in Mild to Moderate Adolescents and Adults Atopic Dermatitis Patients. U.S. National Institutes of Health.
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Emerging drugs for atopic dermatitis. Expert Opin Emerg Drugs. 2009 Mar;14(1):165-79.
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ClinicalTrials.gov (NCT04992546) A Randomized, Intra-patient, Double-blind, Placebo-controlled Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Topically Administered PRN473 (SAR444727) in Patients With Mild to Moderate Atopic Dermatitis. U.S.National Institutes of Health.
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43 |
ClinicalTrials.gov (NCT00882245) Safety and Efficacy of SRD441 Ointment in Patients With Atopic Dermatitis. U.S. National Institutes of Health.
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Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024588)
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ClinicalTrials.gov (NCT00914186) Study of TS-022 in Adult Patients With Atopic Dermatitis With Pruritus (POC). U.S. National Institutes of Health.
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46 |
ClinicalTrials.gov (NCT05277571) A Phase 1/2A, Randomized, Placebo-Controlled, Single-Ascending Dose (Part A, Participant- and Investigator-Blind) and Repeat-Dose (Part B, Participant-, Investigator-, and Sponsor-Blind) Study to Investigate the Safety, Pharmacokinetics, and Efficacy (Part B Only) of UCB1381 in Healthy Study Participants (Part A) and in Study Participants With Moderate to Severe Atopic Dermatitis (Part B). U.S.National Institutes of Health.
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47 |
ClinicalTrials.gov (NCT05656911) A Randomized, Placebo-controlled, Double-blind, Parallel-group, Multicenter Phase 2a Study to Investigate Efficacy and Safety of Zabedosertib (BAY 1834845) for the Treatment of Adult Patients With Moderate-to-severe Atopic Dermatitis. U.S.National Institutes of Health.
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48 |
ClinicalTrials.gov (NCT00932074) A Study to Determine the Safety, Tolerability and Efficacy of KP 13 in Subjects With Atopic Dermatitis(AD). U.S. National Institutes of Health.
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49 |
ClinicalTrials.gov (NCT01605708) Study to Assess the Clinical Activity of a Sequential Dose of REGN846 on Refractory Pruritus in Patients With Atopic Dermatitis. U.S. National Institutes of Health.
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50 |
ClinicalTrials.gov (NCT04668066) A PHASE 1 FIRST IN HUMAN, RANDOMIZED, DOUBLE BLIND, SPONSOR OPEN, PLACEBO-CONTROLLED, SINGLE- AND MULTIPLE DOSE ESCALATION, PARALLEL GROUP STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS AND PHARMACODYNAMICS OF PF 07242813 IN HEALTHY PARTICIPANTS AND PARTICIPANTS WITH ATOPIC DERMATITIS. U.S.National Institutes of Health.
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51 |
ClinicalTrials.gov (NCT05496738) A PHASE 1, RANDOMIZED, DOUBLE-BLIND, SPONSOR-OPEN, PLACEBO-CONTROLLED, DOSE-ESCALATING STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF SINGLE AND MULTIPLE INTRAVENOUS AND SUBCUTANEOUS DOSES OF PF-07264660 IN HEALTHY PARTICIPANTS. U.S.National Institutes of Health.
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52 |
ClinicalTrials.gov (NCT05411588) A PHASE 1, RANDOMIZED, DOUBLE-BLIND, SPONSOR OPEN, PLACEBO-CONTROLLED, DOSE ESCALATING STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF SINGLE AND MULTIPLE INTRAVENOUS AND SUBCUTANEOUS DOSES OF PF-07275315 IN HEALTHY PARTICIPANTS. U.S.National Institutes of Health.
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53 |
ClinicalTrials.gov (NCT05206604) A PHASE 1, RANDOMIZED, DOUBLE-BLIND, SPONSOR-OPEN, VEHICLE-CONTROLLED, FIRST-IN-HUMAN, MULTIPLE-DOSE STUDY, TO INVESTIGATE THE SAFETY, TOLERABILITY, AND PHARMACOKINETICS, OF TOPICALLY ADMINISTERED PF-07295324 AND PF-07259955, IN HEALTHY ADULT PARTICIPANTS. U.S.National Institutes of Health.
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54 |
Clinical pipeline report, company report or official report of Sanofi
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55 |
Clinical pipeline report, company report or official report of Siolta Therapeutics.
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56 |
ClinicalTrials.gov (NCT04643457) A Phase I/IIA, Randomized, Placebo-Controlled, Single-Ascending Dose (Part A, Participant- and Investigator-Blind) and Repeated-Dose (Part B, Participant-, Investigator-, and Sponsor-Blind) Study to Investigate the Safety, Pharmacokinetics, and Efficacy of UCB9741 in Healthy Study Participants (Part A) and in Study Participants With Moderate-to-Severe Atopic Dermatitis (Part B). U.S.National Institutes of Health.
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Protease activated receptor 2 (PAR2) modulators: a patent review (2010-2015).Expert Opin Ther Pat. 2016;26(4):471-83.
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Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006996)
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Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800014452)
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60 |
Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018071)
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61 |
Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008118)
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URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 282).
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The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
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URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2372).
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Effect of orally administered KF66490, a phosphodiesterase 4 inhibitor, on dermatitis in mouse models. Int Immunopharmacol. 2009 Jan;9(1):55-62.
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URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2767).
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Methyl--cyclodextrin treatment combined to incubation with interleukin-4 reproduces major features of atopic dermatitis in a 3D-culture model.Arch Dermatol Res. 2017 Jan;309(1):63-69. doi: 10.1007/s00403-016-1699-7. Epub 2016 Nov 11.
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A Molluscum contagiosum fusion protein inhibits CCL1-induced chemotaxis of cells expressing CCR8 and penetrates human neonatal foreskins: clinical applications proposed.Arch Dermatol Res. 2015 Apr;307(3):275-80. doi: 10.1007/s00403-014-1516-0. Epub 2014 Nov 11.
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CD1a presentation of endogenous antigens by group 2 innate lymphoid cells.Sci Immunol. 2017 Dec 22;2(18):eaan5918. doi: 10.1126/sciimmunol.aan5918.
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Regulation of claudin-4 via p63 in human epithelial cells.Ann N Y Acad Sci. 2017 Oct;1405(1):25-31. doi: 10.1111/nyas.13456. Epub 2017 Aug 30.
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Human Adipose Tissue-Derived Mesenchymal Stem Cells Attenuate Atopic Dermatitis by Regulating the Expression of MIP-2, miR-122a-SOCS1 Axis, and Th1/Th2 Responses.Front Pharmacol. 2018 Nov 6;9:1175. doi: 10.3389/fphar.2018.01175. eCollection 2018.
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A Promoter Polymorphism of the Vitamin D Metabolism Gene Cyp24a1 is Associated with Severe Atopic Dermatitis in Adults.Acta Derm Venereol. 2016 Feb;96(2):169-72. doi: 10.2340/00015555-2226.
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Thymic stromal lymphopoietin epigenetically upregulates Fc receptor subunit-related receptors on antigen-presenting cells and induces T(H)2/T(H)17 polarization through dectin-2.J Allergy Clin Immunol. 2019 Oct;144(4):1025-1035.e7. doi: 10.1016/j.jaci.2019.06.011. Epub 2019 Jun 25.
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Dichotomic nature of atopic dermatitis reflected by combined analysis of monocyte immunophenotyping and single nucleotide polymorphisms of the interleukin-4/interleukin-13 receptor gene: the dichotomy of extrinsic and intrinsic atopic dermatitis.J Invest Dermatol. 2002 Oct;119(4):870-5. doi: 10.1046/j.1523-1747.2002.00191.x.
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MicroRNA-223 is involved in the pathogenesis of atopic dermatitis by affecting histamine-N-methyltransferase.Cell Mol Biol (Noisy-le-grand). 2018 Feb 28;64(3):103-107. doi: 10.14715/cmb/2018.64.3.17.
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Disparity of innate immunity-related gene effects on asthma and allergy on Karelia.Pediatr Allergy Immunol. 2011 Sep;22(6):621-30. doi: 10.1111/j.1399-3038.2011.01186.x. Epub 2011 Jul 13.
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Association of polymorphisms in genes encoding IL-4, IL-13 and their receptors with atopic dermatitis in a Korean population.Exp Dermatol. 2011 Nov;20(11):915-9. doi: 10.1111/j.1600-0625.2011.01357.x. Epub 2011 Sep 14.
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Scratching Counteracts IL-13 Signaling by Upregulating the Decoy Receptor IL-13R2 in Keratinocytes.Int J Mol Sci. 2019 Jul 6;20(13):3324. doi: 10.3390/ijms20133324.
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Interleukin-33 serum levels in postmenopausal women with osteoporosis.Sci Rep. 2019 Mar 7;9(1):3786. doi: 10.1038/s41598-019-40212-6.
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Endoplasmic reticulum aminopeptidase 1 polymorphism Ile276Met is associated with atopic dermatitis and affects the generation of an HLA-C associated antigenic epitope in vitro.J Eur Acad Dermatol Venereol. 2019 May;33(5):906-911. doi: 10.1111/jdv.15449. Epub 2019 Mar 4.
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Ustekinumab treatment in severe atopic dermatitis: Down-regulation of T-helper 2/22 expression.J Am Acad Dermatol. 2017 Jan;76(1):91-97.e3. doi: 10.1016/j.jaad.2016.07.047. Epub 2016 Oct 13.
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Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms.Am J Hum Genet. 2015 Jan 8;96(1):104-20. doi: 10.1016/j.ajhg.2014.12.004.
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Vaccinia virus-specific molecular signature in atopic dermatitis skin.J Allergy Clin Immunol. 2010 Jan;125(1):153-159.e28. doi: 10.1016/j.jaci.2009.10.024.
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Interaction of NPSR1 genotypes and probiotics in the manifestation of atopic eczema in early childhood.Allergol Immunopathol (Madr). 2014 Nov-Dec;42(6):560-7. doi: 10.1016/j.aller.2013.10.001. Epub 2014 Jan 14.
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Neurotensin serum levels and skin gene expression are increased in atopic dermatitis.Br J Dermatol. 2013 Sep;169(3):695-9. doi: 10.1111/bjd.12413.
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Spirodela polyrhiza extract modulates the activation of atopic dermatitis-related ion channels, Orai1 and TRPV3, and inhibits mast cell degranulation.Pharm Biol. 2017 Dec;55(1):1324-1329. doi: 10.1080/13880209.2017.1300819.
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Bee Venom Phospholipase A2 Alleviate House Dust Mite-Induced Atopic Dermatitis-Like Skin Lesions by the CD206 Mannose Receptor.Toxins (Basel). 2018 Apr 2;10(4):146. doi: 10.3390/toxins10040146.
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Usefulness of a global clinical ichthyosis vulgaris scoring system for predicting common FLG null mutations in an adult caucasian population.Br J Dermatol. 2012 Nov;167(5):1165-9. doi: 10.1111/j.1365-2133.2012.11062.x. Epub 2012 Sep 7.
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PGH1, the precursor for the anti-inflammatory prostaglandins of the 1-series, is a potent activator of the pro-inflammatory receptor CRTH2/DP2.PLoS One. 2012;7(3):e33329. doi: 10.1371/journal.pone.0033329. Epub 2012 Mar 19.
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Association analysis of sphingomyelinase 2 polymorphisms for the extrinsic type of atopic dermatitis in Koreans.J Dermatol Sci. 2007 May;46(2):143-6. doi: 10.1016/j.jdermsci.2006.12.001. Epub 2007 Jan 8.
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Lack of primary association between transporter associated with antigen processing genes and atopic dermatitis.J Allergy Clin Immunol. 1995 Dec;96(6 Pt 2):1051-60. doi: 10.1016/s0091-6749(95)70190-7.
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Association of thromboxane A2 receptor (TBXA2R) gene polymorphism in patients with aspirin-intolerant acute urticaria.Clin Exp Allergy. 2011 Feb;41(2):179-85. doi: 10.1111/j.1365-2222.2010.03642.x. Epub 2010 Nov 11.
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LIGHT-HVEM signaling in keratinocytes controls development of dermatitis.J Exp Med. 2018 Feb 5;215(2):415-422. doi: 10.1084/jem.20170536. Epub 2018 Jan 16.
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The Immunosuppressant Macrolide Tacrolimus Activates Cold-Sensing TRPM8 Channels.J Neurosci. 2019 Feb 6;39(6):949-969. doi: 10.1523/JNEUROSCI.1726-18.2018. Epub 2018 Dec 13.
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Serum IL-21 levels are elevated in atopic dermatitis patients with acute skin lesions.Allergol Int. 2017 Jul;66(3):440-444. doi: 10.1016/j.alit.2016.10.010. Epub 2016 Nov 22.
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Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1. Redox Biol. 2020 Jan;28:101321. doi: 10.1016/j.redox.2019.101321. Epub 2019 Sep 5.
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Cordycepin ameliorates skin inflammation in a DNFB-challenged murine model of atopic dermatitis.Immunopharmacol Immunotoxicol. 2018 Oct;40(5):401-407. doi: 10.1080/08923973.2018.1510964. Epub 2018 Sep 5.
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Expression of the collagen VI 5 and 6 chains in normal human skin and in skin of patients with collagen VI-related myopathies.J Invest Dermatol. 2011 Jan;131(1):99-107. doi: 10.1038/jid.2010.284. Epub 2010 Sep 30.
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Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis.Elife. 2019 Oct 21;8:e48448. doi: 10.7554/eLife.48448.
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Signaling via the IL-20 receptor inhibits cutaneous production of IL-1 and IL-17A to promote infection with methicillin-resistant Staphylococcus aureus.Nat Immunol. 2013 Aug;14(8):804-11. doi: 10.1038/ni.2637. Epub 2013 Jun 23.
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Activation of RhoA, Smad2, c-Src, PKC-II/ and JNK in atopic dermatitis.Australas J Dermatol. 2018 Nov;59(4):e258-e261. doi: 10.1111/ajd.12801. Epub 2018 Mar 2.
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ZAG Regulates the Skin Barrier and Immunity in Atopic Dermatitis.J Invest Dermatol. 2019 Aug;139(8):1648-1657.e7. doi: 10.1016/j.jid.2019.01.023. Epub 2019 Feb 6.
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ADAM33 genetic polymorphisms and risk of atopic dermatitis among Japanese children.Clin Biochem. 2009 Apr;42(6):477-83. doi: 10.1016/j.clinbiochem.2008.12.014. Epub 2008 Dec 31.
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Intermedin: a skin peptide that is downregulated in atopic dermatitis.J Invest Dermatol. 2007 Mar;127(3):605-13. doi: 10.1038/sj.jid.5700576. Epub 2006 Sep 28.
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Transcriptomic and lipidomic profiling of eicosanoid/docosanoid signalling in affected and non-affected skin of human atopic dermatitis patients.Exp Dermatol. 2019 Feb;28(2):177-189. doi: 10.1111/exd.13867.
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An aquaporin 3-notch1 axis in keratinocyte differentiation and inflammation.PLoS One. 2013 Nov 8;8(11):e80179. doi: 10.1371/journal.pone.0080179. eCollection 2013.
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Nonclinical Safety and Toxicokinetics of MnTE-2-PyP (BMX-010), a Topical Agent in Phase 2 Trials for Psoriasis and Atopic Dermatitis.Int J Toxicol. 2019 Jul/Aug;38(4):291-302. doi: 10.1177/1091581819852325.
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Glyoxal-induced exacerbation of pruritus and dermatitis is associated with staphylococcus aureus colonization in the skin of a rat model of atopic dermatitis.J Dermatol Sci. 2018 Jun;90(3):276-283. doi: 10.1016/j.jdermsci.2018.02.012. Epub 2018 Feb 21.
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Use of Physcion to Improve Atopic Dermatitis-Like Skin Lesions through Blocking of Thymic Stromal Lymphopoietin.Molecules. 2019 Apr 15;24(8):1484. doi: 10.3390/molecules24081484.
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Development of atopic dermatitis-like skin disease from the chronic loss of epidermal caspase-8.Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22249-54. doi: 10.1073/pnas.1009751108. Epub 2010 Dec 6.
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Increased cardiovascular and atherosclerosis markers in blood of older patients with atopic dermatitis.Ann Allergy Asthma Immunol. 2020 Jan;124(1):70-78. doi: 10.1016/j.anai.2019.10.013. Epub 2019 Oct 14.
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Distinct transcriptomic profiles of early-onset atopic dermatitis in blood and skin of pediatric patients.Ann Allergy Asthma Immunol. 2019 Mar;122(3):318-330.e3. doi: 10.1016/j.anai.2018.11.025. Epub 2018 Dec 1.
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CCL23 expression is induced by IL-4 in a STAT6-dependent fashion.J Immunol. 2007 Apr 1;178(7):4335-41. doi: 10.4049/jimmunol.178.7.4335.
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Investigation of Immune-Regulatory Effects of Mageumsan Hot Spring via Protein Microarray In Vitro.Ann Dermatol. 2018 Jun;30(3):322-330. doi: 10.5021/ad.2018.30.3.322. Epub 2018 Apr 23.
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RANTES gene polymorphisms are not associated with rheumatoid arthritis and atopic dermatitis: a meta-analysis.Int Rev Immunol. 2015;34(6):500-8. doi: 10.3109/08830185.2014.994815. Epub 2015 Jan 21.
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Peroxisome proliferator-activated receptor alpha regulates skin inflammation and humoral response in atopic dermatitis.J Allergy Clin Immunol. 2008 Apr;121(4):962-8.e6. doi: 10.1016/j.jaci.2007.12.1165. Epub 2008 Feb 4.
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The Toll-like receptor 2 R753Q mutation modifies cytokine production and Toll-like receptor expression in atopic dermatitis.J Allergy Clin Immunol. 2008 Apr;121(4):1013-9. doi: 10.1016/j.jaci.2007.11.029. Epub 2008 Jan 30.
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Association study of mast cell chymase polymorphisms with atopy.Allergy. 2005 Oct;60(10):1256-61. doi: 10.1111/j.1398-9995.2005.00879.x.
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Association of cathepsin E deficiency with development of atopic dermatitis.J Biochem. 2003 Dec;134(6):893-902. doi: 10.1093/jb/mvg216.
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A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic dermatitis.J Allergy Clin Immunol. 2017 Apr;139(4):1228-1241. doi: 10.1016/j.jaci.2016.09.052. Epub 2016 Nov 29.
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