General Information of Drug (ID: DMUPCA6)

Drug Name
s-allylglycine
Synonyms
L-Allylglycine; 16338-48-0; (S)-2-aminopent-4-enoic acid; H-Gly(Ally)-OH; (2S)-2-aminopent-4-enoic acid; (S)-(-)-2-Amino-4-pentenoic acid; (S)-2-Amino-4-pentenoic acid; L-alpha-Allyl-Gly; L-2-Amino-4-pentenoic acid; (S)-2-Amino-4- Pentenoic Acid; (S)-ALLYLGLYCINE; 3-VINYL-L-ALANINE; 4-Pentenoic acid, 2-amino-, (2S)-; (2S)-2-amino-4-pentenoic acid; (S)-2-Amino-pent-4-enoic acid; MFCD00002627; s-allylglycine; D-Allylglycine hydrochloride; (-)-Allylglycine; H-Gly(allyl)-OH; (S)-(-)-alpha-Allylglycine, 98%, 98% ee; C5H9NO2
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 115.13
Logarithm of the Partition Coefficient (xlogp) -2.3
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C5H9NO2
IUPAC Name
(2S)-2-aminopent-4-enoic acid
Canonical SMILES
C=CC[C@@H](C(=O)O)N
InChI
InChI=1S/C5H9NO2/c1-2-3-4(6)5(7)8/h2,4H,1,3,6H2,(H,7,8)/t4-/m0/s1
InChIKey
WNNNWFKQCKFSDK-BYPYZUCNSA-N
Cross-matching ID
PubChem CID
167529
CAS Number
16338-48-0
TTD ID
D09OTM

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glutamate decarboxylase 2 (GAD2) TT7UY6K DCE2_HUMAN Inhibitor [2]
Glutamic acid decarboxylase 1 (GAD1) TTKGEP3 DCE1_HUMAN Inhibitor [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5267).
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1273).
3 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1272).