Details of Disease

General Information of Disease (ID: DIS5O9P9)

Disease Name Ventilator-associated pneumonia
Disease Class PK80-PK81: Medical/surgical procedure injury
Disease Hierarchy
DIS01GPL: Grass pollen hypersensitivity
DIS5O9P9: Ventilator-associated pneumonia
ICD Code
ICD-11
ICD-11: PK81.0

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 1 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Cefiderocol DMJSMDL Approved Small molecular drug [1]
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This Disease is Treated as An Indication in 7 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
AR-301 DM2YQK8 Phase 3 Antibody [2]
Murepavadin DMUQ390 Phase 3 NA [3]
MEDI4893 DMXB4NL Phase 2b Antibody [4]
ASN100 DMWPGLS Phase 2 Monoclonal antibody [5]
MEDI3902 DMOXKIC Phase 2 Antibody [6]
Panobacumab DMV27SP Phase 2 Monoclonal antibody [7]
KBP-7072 DMXJDXH Phase 1 Small molecular drug [8]
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⏷ Show the Full List of 7 Drug(s)

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2020
2 ClinicalTrials.gov (NCT03816956) Adjunctive Therapy to Antibiotics in the Treatment of S. Aureus Ventilator-Associated Pneumonia With AR-301 (AR-301-002). U.S. National Institutes of Health.
3 Anti-ageing pipeline starts to mature.Nat Rev Drug Discov. 2018 Sep;17(9):609-612.
4 ClinicalTrials.gov (NCT02296320) Study of the Efficacy and Safety of MEDI4893
5 ClinicalTrials.gov (NCT02940626) Prevention of S. Aureus Pneumonia Study in Heavily Colonized, Mechanically Ventilated Subjects
6 ClinicalTrials.gov (NCT02696902) Effort to Prevent Nosocomial Pneumonia Caused by Pseudomonas Aeruginosa in Mechanically Ventilated Subjects
7 ClinicalTrials.gov (NCT00851435) Safety and Pharmacokinetics of KBPA-101 in Hospital Acquired Pneumonia Caused by O11 Pseudomonas Aeruginosa. U.S. National Institutes of Health.
8 ClinicalTrials.gov (NCT04532957) A Multiple Ascending Dose Study to Investigate Safety of KBP-7072 in Healthy Subjects. U.S. National Institutes of Health.