General Information of Drug (ID: DMW7L0Y)

Drug Name
PUL-042
Synonyms ODN-M362/Pam2CSK4; Pam2-ODN; Pam2/ODN; Pam2CSK4/ODN-M362; PUL-042
Indication
Disease Entry ICD 11 Status REF
Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 2 [1]
Therapeutic Class
Antiviral Agents
Drug Type
Protein/peptide drug
Structure 3D Structure is Not Available
3D MOL is unavailable 2D MOL
Cross-matching ID
TTD ID
D0BR8X

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
HUMAN toll-like receptor 2 (TLR2) TTAVUMS TLR2_HUMAN Agonist [2]
HUMAN toll-like receptor 6 (TLR6) TTLSU52 TLR6_HUMAN Agonist [2]
HUMAN toll-like receptor 9 (TLR9) TT2LBCR TLR9_HUMAN Agonist [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT04312997) The Use of PUL-042 Inhalation Solution to Reduce the Severity of COVID-19 in Adults Positive for SARS-CoV-2 Infection. U.S. National Institutes of Health.
2 Pulmotects lead product, PUL-042, is a clinical stage inhaled therapeutic that in preclinical studies stimulates the innate immune system in minutes to provide immediate and effective protection against all major classes of pathogens that lasts for days.