Details of the Drug

General Information of Drug (ID: DMXHWK6)

Drug Name
Neutralase
Synonyms Heparinase I, IBEX
Indication
Disease Entry ICD 11 Status REF
Angiogenesis disorder BE2Z Discontinued in Phase 3 [1]
Cross-matching ID
TTD ID
D0G9LP

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Heparanase (HPSE) TTR7GJO HPSE_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Angiogenesis disorder
ICD Disease Classification BE2Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Heparanase (HPSE) DTT HPSE 8.10E-01 0.19 0.23
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007559)
2 Heparanase neutralizes the anticoagulation properties of heparin and low-molecular-weight heparin. J Thromb Haemost. 2006 Mar;4(3):560-5.