Details of the Drug

General Information of Drug (ID: DMZ5A6D)

Drug Name
GSK2398852
Synonyms 2398852
Indication
Disease Entry ICD 11 Status REF
Amyloidosis 5D00 Phase 1 [1]
Drug Type
Antibody
Cross-matching ID
TTD ID
D07LBQ
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Serum amyloid P-component (APCS) TTB7VAT SAMP_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Amyloidosis
ICD Disease Classification 5D00
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Serum amyloid P-component (APCS) DTT APCS 3.02E-01 -0.06 -0.21
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8255).
2 ClinicalTrials.gov (NCT01777243) A Study to Evaluate the Safety of GSK2398852 When Co-administered With GSK2315698 in Patients With Systemic Amyloidosis. U.S. National Institutes of Health.