Details of the Drug

General Information of Drug (ID: DMZAQS8)

Drug Name
ION464
Synonyms BIIB101
Indication
Disease Entry ICD 11 Status REF
Multiple system atrophy 8D87.0 Phase 1 [1]
Parkinson disease 8A00.0 Phase 1 [1]
Drug Type
Antisense oligonucleotide
Cross-matching ID
TTD ID
D23VYO
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
SNCA messenger RNA (SNCA mRNA) TTPO9ZI SYUA_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT04165486) A Phase 1 Study to Assess the Safety, Tolerability, and Pharmacokinetics of ION464 Administered Intrathecally to Adults With Multiple System Atrophy. U.S.National Institutes of Health.
2 Clinical pipeline report, company report or official report of Ionis