Details of the Drug

General Information of Drug (ID: DMZUA5C)

Drug Name

MK-6302

Synonyms

INS-20; Pegylated GCSF, Insmed/Merck

Indication

Disease Entry	ICD 11	Status	REF
Neutropenia	4B00.0	Phase 1	[1]
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Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Granulocyte colony-stimulating factor receptor (G-CSF-R)	TTC70AJ	CSF3R_HUMAN	Modulator	[2]

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Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Neutropenia

ICD Disease Classification

4B00.0

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Granulocyte colony-stimulating factor receptor (G-CSF-R)	DTT	CSF3R	2.08E-08	0.36	0.96

Molecular Expression Atlas (MEA)

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References

1	Clinical pipeline report, company report or official report of Merck.
2	Merck ditches biogeneric. Nat Biotechnol. 2010 Jul;28(7):636.