Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DME (ID: DE0K82S)

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Approved Drug(s)

Download the Complete Related Drug List

3 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Niclosamide	DMJAGXQ	Cestodes infection	1F70-1F76	Approved	[1]
Nitrazepam	DMEGIQ6	Epilepsy	8A60-8A68	Approved	[2], [3]
Riboflavin	DM8YMWE	Acne vulgaris	ED80	Approved	[2], [3]
------------------------------------------------------------------------------------

2 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Mononitrophenol	DM4QO9G	N. A.	N. A.	Investigative	[2], [3]
Nitrobenzoate	DM6FVHC	N. A.	N. A.	Investigative	[2], [3]
------------------------------------------------------------------------------------

Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	CYP1A1 and Cnr nitroreductase bioactivated niclosamide in vitro. Mutagenesis. 2013 Nov;28(6):645-51.
2	Purification and characterization of wild-type and mutant "classical" nitroreductases of Salmonella typhimurium. L33R mutation greatly diminishes binding of FMN to the nitroreductase of S. typhimurium. J Biol Chem. 1998 Sep 11;273(37):23922-8.
3	Prenatal diagnosis of junctional epidermolysis bullosa Herlitz type. Lancet. 1989 Oct 28;2(8670):1035-6. Letter